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| Nogueira,Susie A.; Abreu,Thalita; Oliveira,Ricardo; Araújo,Lúcia; Costa,Tomaz; Andrade,Miriam; Psic,M. Fátima Garcia; Machado,Elizabeth; Rodrigues,Káris; Mercadante,Elizabeth Regina; Fernandes,Iraína; Sapia,M. Conceição; Lambert,John S.. |
| OBJECTIVES: To determine the HIV vertical transmission rate (VTR) and associated risk factors by use of zidovudine and infant care education in Brazil. METHODS: Since 1995, a prospective cohort of HIV infected pregnant women has been followed at the Federal University of Rio de Janeiro. A multidisciplinary team was established to implement the best available strategy to prevent maternal-infant HIV transmission. Patients with AIDS or low CD4 and high viral load received anti-retroviral drugs in addition to zidovudine. Children were considered infected if they had 2 positive PCR-RNA tests between 1 and 4 months of age, or were HIV antibody positive after 18 months. Education regarding infant treatment and use of formula instead of breast feeding was... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Brazil; HIV; Prevention; Perinatal transmission; Zidovudine. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702001000200006 |
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| Coelho,Antonio Victor Campos; Coelho,Hemílio Fernandes Campos; Arraes,Luiz Cláudio; Crovella,Sergio. |
| Abstract HIV-1 mother-to-child transmission (HIV-1 MTCT), is an important cause of children mortality worldwide. Brazil has been traditionally praised by its HIV/Aids program, which provides free-of-charge care for people living with HIV-1. Using public epidemiology and demographic databases, we aimed at modeling HIV-1 MTCT prevalence in Brazil through the years (1994-2016) and elaborate a statistical model for forecasting, contributing to HIV-1 epidemiologic surveillance and healthcare decision-making. We downloaded sets of live births and mothers' data alongside HIV-1 cases notification in children one year old or less. Through time series modeling, we estimated prevalence along the years in Brazil, and observed a remarkable decrease of HIV-1 MTCT... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HIV-1; Vertical transmission; Perinatal transmission; Biostatistics; Epidemiology; Forecasting. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702019000400218 |
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