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| Vieira,Juliana; Matsuzaki,Patricia; Nagamine,Márcia Kazumi; Haraguchi,Mitsue; Akisue,Gokithi; Gorniak,Silvana Lima; Dagli,Maria Lúcia Zaidan. |
| This study aimed to investigate the effects of the administration of butanolic residue (BR) of Pfaffia paniculata by intraperitoneal route to Ehrlich ascitis tumor bearing mice. Initially, a toxicity study of P. paniculata BR was performed in which doses of 12.5; 25 and 50mg/Kg were administered by intraperitoneal injection for seven days to Swiss mice. The treatment did not show toxicity. Then, Swiss male mice received, by intraperitoneal injection, once a day, 12.5; 25 or 50mg/Kg of P. paniculata BR for seven days. This protocol started in the same day of tumor inoculation with 5X10(6) cells i.p. The treatment with butanolic residue of P.paniculata i.p caused a significant increase in the ascitic volume; however, a significant decrease in tumor cells... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Pfaffia paniculata; Ehrlich; Intraperitoneal treatment. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132010000300014 |
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