|
|
|
|
|
| CARDOTE,TERESA A.F.; BARATA,JOANA F.B.; AMADOR,CAROLINA; ALVES,ELIANA; NEVES,MARIA GRAÇA P.M.S.; CAVALEIRO,JOSÉ A.S.; CUNHA,ÂNGELA; ALMEIDA,ADELAIDE; FAUSTINO,MARIA AMPARO F.. |
| ABSTRACT Cationic derivatives of 5,10,15-tris[4-(pyridin-4-ylsulphanyl)-2,3,5,6-tetrafluorophenyl]-corrolategallium(III)pyridine and 5,10,15-tris[4-(pyridin-2-ylsulfanyl)-2,3,5,6-tetrafluorophenyl]-correlategallium(III)pyridine were synthesized and their photosensitizing properties against the naturally bioluminescent Gram-negative bacterium Allivibrio fischeri were evaluated. The cationic corrole derivatives exhibited antibacterial activity at micromolar concentrations against this Gram-negative bacterium strain. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Allivibrio fischeri; Corroles; Photosensitizer; PDI; Bioluminescence. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000301175 |
| |
|
|
| Muehlmann,L.A.; Joanitti,G.A.; Silva,J.R.; Longo,J.P.F.; Azevedo,R.B.. |
| Photodynamic therapy is a well-established and clinically approved treatment for several types of cancer. Antineoplastic photodynamic therapy is based on photosensitizers, i.e., drugs that absorb photons translating light energy into a chemical potential that damages tumor tissues. Despite the encouraging clinical results with the approved photosensitizers available today, the prolonged skin phototoxicity, poor selectivity for diseased tissues, hydrophobic nature, and extended retention in the host organism shown by these drugs have stimulated researchers to develop new formulations for photodynamic therapy. In this context, due to their amphiphilic characteristic (compatibility with both hydrophobic and hydrophilic substances), liposomes have proven to be... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Photodynamic therapy; Liposome; Antineoplastic therapy; Cancer; Photosensitizer. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000800001 |
| |
|
|
|
