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| Coussot, Gaelle; Le Postollec, Aurelie; Faye, Clement; Baque, Mickael; Vandenabeele-trambouze, Odile; Incerti, Sebastien; Vigier, Flavie; Chaput, Didier; Cottin, Herve; Przybyla, Bartos; Berger, Thomas; Dobrijevic, Michel. |
| Antibody-based analytical instruments are under development to detect signatures of life on planetary bodies. Antibodies are molecular recognition reagents able to detect their target at sub-nanomolar concentrations, with high affinity and specificity. Studying antibody binding performances under space conditions is mandatory to convince space agencies of the adequacy of this promising tool for planetary exploration. To complement previous ground-based experiments on antibody resistance to simulated irradiation, we evaluate in this paper the effects of antibody exposure to real space conditions during the EXPOSE-R2 mission outside the International Space Station. The absorbed dose of ionizing radiation recorded during the 588 days of this mission (220 mGy)... |
| Tipo: Text |
Palavras-chave: Astrobiology; Cosmic rays; Biochip; Antibody; Planetary exploration. |
| Ano: 2019 |
URL: https://archimer.ifremer.fr/doc/00601/71305/69721.pdf |
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