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Cytotoxicity and antiviral activity evaluation of Cymbopogon spp hydroethanolic extracts BJPS
Chiamenti,Lisandra; Silva,Francini Pereira da; Schallemberger,Karoline; Demoliner,Meriane; Rigotto,Caroline; Fleck,Juliane Deise.
Cymbopogon citratus and C. nardus are noteworthy among the several existing plant species displaying medicinal properties, due to the potential pharmacological activity of these species, including antiviral, antibacterial, antifungal and anti-trypanosomal activities. The objective of this study was to carry out in vitro toxicity tests of plant extracts from both species and analyze potential antiviral activity against Human mastadenovirus serotype 5 (HAdV-5). Two cell lines (A549 and VERO) were used and mitochondrial and lysosomal viability were determined by the MTT and neutral red assay, respectively, after two exposure times (24 hours and six days). The aim of these assays was to counteract the behavior of the extracts against the different cell lines...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cymbopogon citratus/toxicity; Cymbopogon nardus/toxicity; Cellular viability; Human mastadenovirus; Plants/extracts..
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502019000100539
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