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| NASCIMENTO,DAYANE K.D.; SOUZA,IVONE A. DE; OLIVEIRA,ANTÔNIO F.M. DE; BARBOSA,MARIANA O.; SANTANA,MARLLON A.N.; PEREIRA JÚNIOR,DANIEL F.; LIRA,EDUARDO C.; VIEIRA,JEYMESSON R.C.. |
| ABSTRACT Mangroves represent areas of high biological productivity and it is a region rich in bioactive substances used in medicine production. Conocarpus erectus (Combretaceae) known as button mangrove is one of the species found in mangroves and it is used in folk medicine in the treatment of anemia, catarrh, conjunctivitis, diabetes, diarrhea, fever, gonorrhea, headache, hemorrhage, orchitis, rash, bumps and syphilis. The present study aimed to investigate the acute toxicity of aqueous extract of leaves of C. erectus in Swiss albino mice. The plant material was collected in Vila Velha mangroves, located in Itamaracá (PE). The material was subjected to a phytochemical screening where extractive protocols to identify majority molecules present in leaves... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Acute toxicity; Aqueous extract; Conocarpus erectus; Medicinal plants; Plants extracts. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000401431 |
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| BOVERIS,ALEJANDRO D; GALATRO,ANDREA; PUNTARULO,SUSANA. |
| The antioxidant ability of nitric oxide (NO) generated by a chemical donor and of commercially available antioxidant preparations was assayed. SNAP (S-Nitroso-N-acetylpenicilamine) was used as the NO donor, and Ginkgo biloba, wheat and alfalfa preparations were tested. Lipid peroxidation was assayed by EPR employing a reaction system consisting of rat liver microsomes, ADP, FeCl3, NADPH and POBN in phosphate buffer, pH=7.4. In vitro NO exposure decreased microsomal lipid peroxidation in a dose-dependent manner. The dose responsible for inhibiting the microsomal content of lipid radical adducts by 50% (LD50) for SNAP was 550 mu M (NO generation rate 0.1 mu M/min). The addition of 50 mM hemoglobin to the incubation media prevented NO effect on lipid... |
| Tipo: Journal article |
Palavras-chave: Antioxidants; Nitric oxide; Plants extracts; Lipid radicals. |
| Ano: 2000 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602000000200016 |
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