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| Khatoon,Lubna; Baliraine,Frederick N.; Malik,Salman A.; Yan,Guiyun. |
| Plasmodium vivax and Plasmodium falciparum are becoming resistant to drugs including antifolates, sulphonamides and chloroquine. This study was focused at sequence analysis of resistant genes of these parasites against sulphadoxine-pyrimethamine and chloroquine, from Bannu, Pakistan. Known mutations were detected at codons 57, 58 and 117 of pvdhfr gene of P. vivax, while none of the isolates had any pvdhps mutation. Similarly P. falciparum isolates exhibited double 59R + 108N mutations in pfdhfr, and single 437G in pfdhps thus demonstrating the existance of triple mutant 59R + 108N + 437G haplotype in this region. The key chloroquine resistance mutation, 76T in pfcrt was observed in 100% of the P. falciparum isolates, with haplotype SVMNT which is also... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Plasmodium vivax; Plasmodium falciparum; Sequence analysis; Pakistan. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000500013 |
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| Khatoon,Lubna; Khan,Inam Ullah; Shah,Shahid Ali; Jan,Muhammad Ishtiaq; Ullah,Farhat; Malik,Salman Akbar. |
| Malaria is one of the serious diseases threatening human health in Pakistan and contributes to a large proportion of the total malaria deaths in South Asia. However, little is known about the nature and extent of genetic diversity of the malarial parasites circulating in Pakistan. This study was designed to assess the infection status of Plasmodium and the genetic diversity of Plasmodium vivax and Plasmodium falciparum by analyzing msp-3α, msp-3β and msp-1, msp-2 genes respectively using allele specific nested PCR and RFLP assays. For this purpose, 130 field isolates were collected from the individuals who exhibited clinical symptoms associated with malaria in the Kohat region of Khyber Pakhtoonkhwa (KPK), Pakistan. Among 130 blood samples collected, P.... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Plasmodium vivax; Plasmodium falciparum; Genetic variation; Pakistan. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000200014 |
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| Tarazona,Alonso Soto; Zerpa,Lely Solari; Mendoza Requena,Daniel; Llanos-Cuentas,Alejandro; Magill,Allan. |
| OBJECTIVE: To determine the sensitivity and specificity of the rapid diagnostic test OptiMAL® for diagnosis of Plasmodium vivax malaria. MATERIAL AND METHODS: We included all the patients who sought medical attention in the San Martin Pangoa Hospital, Junin, an area endemic for vivax malaria in Peru, between October and December 1998, who had fever during the previous 72 hours and who were older than 12 months. The gold standard for diagnosis was thick blood film microscopy. We determined the parasitemia rate for each of the positive slides. We calculated sensitivity, specificity, positive predictive value and negative predictive value of the test. RESULTS: We included 72 patients; 39 of them were positive for P. vivax by microscopic examination. The... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: OptiMAL; Malaria; Plasmodium vivax; Diagnosis; Dipstick. |
| Ano: 2004 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702004000200005 |
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| Lomar,André V.; Vidal,José E.; Lomar,Frederico P.; Barbas,Carmen Valente; Matos,Gustavo Janot de; Boulos,Marcos. |
| Severe pulmonary involvement in malaria has been frequently reported in cases of Plasmodium falciparum infection, but rarely in vivax malaria. Among the 11 previous cases of vivax-related severe respiratory involvement described in the literature, all except one developed it after the beginning of anti-malarial treatment; these appear to correspond to an exacerbation of the inflammatory response. We report the case of a 43-year-old Brazilian woman living in a malaria-endemic area, who presented acute respiratory distress syndrome (ARDS) caused by P. vivax before starting anti-malarial treatment. The diagnosis was made based on microscopic methods. A negative rapid immunochromatographic assay, based on the detection of Histidine Rich Protein-2 (HRP-2) of P.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Malaria; Plasmodium vivax; Acute respiratory distress syndrome; Acute respiratory failure; Brazil. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000500011 |
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| Mosnier, Emilie; Dusfour, Isabelle; Lacour, Guillaume; Saldanha, Raphael; Guidez, Amandine; Gomes, Margarete S.; Sanna, Alice; Epelboin, Yanouk; Restrepo, Johana; Davy, Damien; Demar, Magalie; Djossou, Félix; Douine, Maylis; Ardillon, Vanessa; Nacher, Mathieu; Musset, Lise; Roux, Emmanuel. |
| Background In 2017, inhabitants along the border between French Guiana and Brazil were affected by a malaria outbreak primarily due to Plasmodium vivax (Pv). While malaria cases have steadily declined between 2005 and 2016 in this Amazonian region, a resurgence was observed in 2017. Methods Two investigations were performed according to different spatial scales and information details: (1) a local study on the French Guiana border, which enabled a thorough investigation of malaria cases treated at a local village health center and the entomological circumstances in the most affected neighborhood, and (2) a regional and cross-border study, which enabled exploration of the regional spatiotemporal epidemic dynamic. Number and location of malaria cases were... |
| Tipo: Text |
Palavras-chave: Plasmodium vivax; Anopheles darlingi; French Guiana; Brazil; Transnational; Outbreak investigation; Indigenous south Americans; Malaria; Amazonia. |
| Ano: 2020 |
URL: https://archimer.ifremer.fr/doc/00632/74387/74081.pdf |
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