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Yamamoto,Marcos Kazuo; Novelli,Moacyr Domingos; Corrêa,Luciana; de Sousa,Suzana Cantanhede M; Luz,João Gualberto C. |
Opinions about the clinical utility of platelet-rich plasma (PRP) vary, as a large number of experimental studies have questioned its efficacy. The purpose of this study was to evaluate the effects of PRP on experimental alveolar wound healing in rats. Fifty young adult male Wistar rats were divided in control and PRP groups and submitted to extraction of the right maxillary incisor. In the PRP group, blood was collected by cardiac puncture, and the socket was filled with a PRP gel. Animals were euthanized after 1, 3, 7, 14 and 30 days. Histological and histomorphometric analyses were performed at each experimental time point. Semiquantitative histological analysis showed that the PRP group exhibited significantly more collagen-matrix deposition and less... |
Tipo: Journal article |
Palavras-chave: Tooth socket; Wound healing; Platelet-rich plasma; Animal experimentation. |
Ano: 2017 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022017000100041 |
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Abouelnasr, Khaled; Hamed, Mohamed; Lashen, Samah; El-Adl, Mohamed; Rasha, Eltaysh; Tagawa, Michihito. |
Platelet-rich plasma (PRP) has an important role in musculoskeletal surgery; however, it has been underutilized for accelerating the healing of abdominal wall defects in veterinary practice. Therefore, the aim of this study was to evaluate the use of commercial polyester/cotton fabric (Damour) as a new composite mesh for the repair of experimentally induced abdominal wall defects in canine models, and to investigate the possible role of PRP for improving such repair and reducing allied complications. For this purpose, abdominal wall defects were created in 24 healthy mongrel dogs and then repaired with mesh alone (control group) or mesh and allogenic PRP (PRP group). Dogs were euthanized after 2 or 4 months for gross examination of implantation site,... |
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Palavras-chave: Abdominal wall defect; Damour; Dog; Platelet-rich plasma. |
Ano: 2017 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4542 |
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