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Prevalence, predictors and outcomes of potential drug-drug interactions in left ventricular failure: considerable factors for quality use of medicines BJPS
Haq,Inamul; Ismail,Mohammad; Khan,Fahadullah; Khan,Qasim; Ali,Zahid; Noor,Sidra.
Hospitalized patients with left ventricular failure (LVF) are at high risk for potential drug-drug interactions (pDDIs) and its related adverse effects owing to multiple risk factors such as old age, comorbidities and polypharmacy. This cross-sectional study conducted in two tertiary care hospitals aim to identify frequency, levels and predictors of pDDIs in LVF patients. Data about patients’ demographic, hospital stay, medication therapy, sign/symptoms and laboratory test results were collected for 385 patients with LVF. Micromedex Drug-Reax® was used to screen patients’ medication profiles for pDDIs. Overall prevalence and severity-wise prevalence of pDDIs were identified. Chi-square test was performed for comparative analysis of various variables....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Left ventricular failure; Heart diseases; Potential drug-drug interactions; Drug interactions; Patients safety; Rational drug use.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100589
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Prevalence of potential drug-drug interactions in the intensive care unit of a Brazilian teaching hospital BJPS
Rodrigues,Aline Teotonio; Stahlschmidt,Rebeca; Granja,Silvia; Pilger,Diogo; Falcão,Antonio Luis Eiras; Mazzola,Priscila Gava.
Abstract Patients in intensive care unit are prescribed large numbers of drugs, highlighting the need to study potential Drug-Drug Interactions in this environment. The aim of this study was to delineate the prevalence and risk of potential drug-drug interactions between medications administered to patients in an ICU. This cross-sectional observational study was conducted during 12 months, in an adult ICU of a teaching hospital. Inclusion criteria were: prescriptions with 2 or more drugs of patients admitted to the ICU for > 24 hours and age of ≥18 years. Potential Drug-Drug Interactions were quantified and classified through MicromedexTM database. The 369 prescriptions included in this study had 205 different drugs, with an average of 13.04 ± 4.26...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Potential drug-drug interactions; Intensive care unit; Patient safety; University hospitals..
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000100624
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