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	Provedor de dados BABT (1) International Journal of Morphology (1) Autor Aguirre -Samudio,Ana Julia (1) Castro,V. L. (1) Márquez-Orozco,Amalia (1) Márquez-Orozco,María Cristina (1) Paraíba,L. C. (1) Tambasco,A. J. (1) Tambasco,D. D. (1) de la Fuente-Juárez,Graciela (1) Mais... Palavra-chave Prenatal exposure (2) Atretic follicles (1) Benzodiazepine (1) Corpus luteum (1) Flunitrazepam (1) Genetic evaluation (1) Mancozeb (1) Postnatal development (1) Rats (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Journal article (1) Ano 2006 (1) 1999 (1) País Brazil (1) Chile (1) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Histological Changes of the Ovary of Adult Mice Exposed Prenatally to Flunitrazepam International Journal of Morphology Aguirre -Samudio,Ana Julia; de la Fuente-Juárez,Graciela; Márquez-Orozco,Amalia; Márquez-Orozco,María Cristina. Flunitrazepam (FNZ) is a minor tranquillizer involving allosteric modulation of the GABA receptor complex. It is a ligand of the peripheral benzodiazepine receptor (PBR) that participates in cholesterol transport in steroidogenic organs. The purpose was to investigate whether a single oral dose of FNZ of 2.5 mg/kg of body weight (bw), administered on day 6 of gestation, alters the structure of the adult ovary of mouse offsprings at 2 months of age. The mouse offsprings of the in utero FNZ-treated group and those of the control group (C) were killed. Ovaries were obtained in early estrous, fixed in Zenker solution, and processed by routine histological techniques. Serial sections were observed under light microscopy to determine the characteristics and... Tipo: Journal article Palavras-chave: Benzodiazepine; Flunitrazepam; Atretic follicles; Corpus luteum; Prenatal exposure. Ano: 2006 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022006000500022 Cytogenetic and teratological effects of mancozeb pre natal exposure on rats BABT Castro,V. L.; Tambasco,A. J.; Paraíba,L. C.; Tambasco,D. D.. Studies were conducted on the dam’s fertility and pup viability, litter physical and motor development and chromosomal analysis with female rats exposed to different concentrations of mancozeb, at initial and organogenesis periods of pregnancy. The exposure did not interfere with the pregnant females or their estrous cycle but resulted in retarded physical development, with exception of the vaginal opening and tests descent; which were in advance. The litter body weight was not affected. The examination of swimming performance indicated an initial impairment and a posterior recovery. The observed chromosome damage in dams and pups was found to enhance with the fungicide’s concentration. The results obtained led to the conclusion that even in the absence of... Tipo: Info:eu-repo/semantics/article Palavras-chave: Mancozeb; Rats; Postnatal development; Prenatal exposure; Genetic evaluation. Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89131999000200001 Registros recuperados: 2 Primeira ... 1 ... Última

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