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	Provedor de dados BJMBR (1) Autor Cui,Yan (1) Li,Na (1) Liu,Feng (1) Yin,Min (1) Palavra-chave Chronic kidney disease (1) Long non-coding RNAs (1) Prognostic biomarkers (1) WGCNA (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2019 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Screening potential prognostic biomarkers of long non-coding RNAs for predicting the risk of chronic kidney disease BJMBR Li,Na; Cui,Yan; Yin,Min; Liu,Feng. Not much is known about the roles of long non-coding RNAs (lncRNAs) for chronic kidney disease (CKD). In this study, we included CKD patient cohorts and normal controls as a discovery cohort to identify putative lncRNA biomarkers associated with CKD. We first compared the lncRNA expression profiles of CKD patients with normal controls, and identified differentially expressed lncRNAs and mRNAs. Co-expression network based on the enriched differentially expressed mRNAs and lncRNAs was constructed using WGCNA to identify important modules related to CKD. A lncRNA-miRNA-mRNA pathway network based on the hub lncRNAs and mRNAs, related miRNAs, and overlapping pathways was further constructed to reveal putative biomarkers. A total of 821 significantly... Tipo: Info:eu-repo/semantics/article Palavras-chave: Long non-coding RNAs; Chronic kidney disease; WGCNA; Prognostic biomarkers. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019001100608 Registros recuperados: 1 Primeira ... 1 ... Última

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