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Cost-effectiveness of insulin analogs from the perspective of the Brazilian public health system BJPS
Cazarim,Maurílio de Souza; Rodrigues,João Paulo Vilela; Cruz-Cazarim,Estael Luzia Coelho da; Ayres,Lorena Rocha; Pereira,Leonardo Régis Leira.
ABSTRACT Human insulin is provided by the Brazilian Public Health System (BPHS) for the treatment of diabetes, however, legal proceedings to acquire insulin analogs have burdened the BPHS health system. The aim of this study was to perform a cost-effectiveness analysis to compare insulin analogs and human insulins. This is a pharmacoeconomic study of cost-effectiveness. The direct medical cost related to insulin extracted from the Ministry of Health drug price list was considered. The clinical results, i.e. reduction in glycated hemoglobin (HbA1c), were extracted by meta-analysis. Different scenarios were structured to measure the uncertainties regarding the costs and reduction in HbA1c. Decision tree was developed for sensitivity of Incremental Cost...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Diabetes Mellitus/treatment/cost-effectiveness/evaluation; Prolonged Action Insulin; Short Action Insulin; Brazilian Public Health System.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000300616
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