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| Marzolo,María-Paz; Farfán,Pamela. |
| Since the discovery of the low-density lipoprotein receptor (LDLR) and its association with familial hypercholesterolemia in the early 1980s, a family of structurally related proteins has been discovered that has apolipoprotein E as a common ligand, and the broad functions of its members have been described. LRP2, or megalin, is a member of the LDLR family and was initially called gp330. Megalin is an endocytic receptor expressed on the apical surface of several epithelial cells that internalizes a variety of ligands including nutrients, hormones and their carrier proteins, signaling molecules, morphogens, and extracellular matrix proteins. Once internalized, these ligands are directed to the lysosomal degradation pathway or transported by transcytosis... |
| Tipo: Journal article |
Palavras-chave: Alzheimer's Disease; Cubilin; Diabetic nephropathy; FXR; Gallstone disease; GSK3; Lowe syndrome; Megalin; PPAR; RAP; Regeneration. |
| Ano: 2011 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602011000100012 |
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| Miyahira,Igor Christo; Carneiro,Jéssica Beck; Gonçalves,Isabela Cristina Brito; Lacerda,Luiz Eduardo Macedo de; Oliveira,Jaqueline Lopes de; Vasconcelos,Mariana Castro de; Santos,Sonia Barbosa dos. |
| Abstract The Guandu River Basin is extremely important to state of Rio de Janeiro, as a water supplier of several municipalities. However, the malacological knowledge and environmental status is not well known to this basin. The aim of this paper is to present an inventory of freshwater mollusks, as well as an environmental assessment through a Rapid Assessment Protocol, of ten sampling sites at Guandu River basin in six municipalities (Piraí, Paracambi, Japeri, Seropédica, Queimados and Nova Iguaçu). Thirteen species of molusks were found, eight native (Pomacea maculata, Biomphalaria tenagophila, Gundlachia ticaga, Gundlachia radiata, Omalonyx matheroni, Diplodon ellipticus, Anodontites trapesialis and Eupera bahiensis) and five exotics (Melanoides... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Gastropoda; Bivalvia; Mollusca; Exotic species; RAP. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-06032017000300305 |
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