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	Provedor de dados BJMBR (2) Biol. Res. (1) Autor ALGARÍN,CECILIA R (1) Alvariño,F. (1) Jantos,H. (1) Monti,D. (1) Monti,J.M. (1) PEIRANO,PATRICIO D (1) Peres,C.A. (1) Pinto Jr.,L.R. (1) Remesar-Lopez,A.J. (1) Russo,R.H. (1) Tufik,S. (1) Mais... Palavra-chave REM sleep (3) Benzodiazepine1 receptor (1) Brain development (1) Brain plasticity (1) Dopaminergic receptors (1) Haloperidol (1) Introducing sleep (1) Light-dark cycle (1) NREM sleep (1) Rapid eye movements (1) SX-3228 (1) Sawtooth waves (1) Sleep (1) Sleep deprivation (1) Sleep development (1) Waking (1) Zolpidem (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Journal article (1) Ano 2007 (1) 2002 (1) 1999 (1) País Brazil (2) Chile (1) Idioma Inglês (3)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 3 Primeira ... 1 ... Última Sleep in brain development Biol. Res. PEIRANO,PATRICIO D; ALGARÍN,CECILIA R. With the discovery of rapid eye movement (REM) sleep, sleep was no longer considered a homogeneous state of passive rest for the brain. On the contrary, sleep, and especially REM sleep, appeared as an active condition of intense cerebral activity. The fact that we get large amounts of sleep in early life suggested that sleep may play a role in brain maturation. This idea has been investigated for many years through a large number of animal and human studies, but evidence remains fragmented. The hypothesis proposed was that REM sleep would provide an endogenous source of activation, possibly critical for structural maturation of the central nervous system. This proposal led to a series of experiments looking at the role of REM sleep in brain development. In... Tipo: Journal article Palavras-chave: Sleep development; Brain development; Brain plasticity; NREM sleep; REM sleep; Introducing sleep. Ano: 2007 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602007000500008 Effect of SX-3228, a selective ligand for the BZ1 receptor, on sleep and waking during the light-dark cycle in the rat BJMBR Alvariño,F.; Monti,J.M.; Jantos,H.; Monti,D.. The effects of the benzodiazepine1 (BZ1) receptor agonist SX-3228 were studied in rats (N = 12) implanted for chronic sleep procedures. Administration of 0.5, 1.0 and 2.5 mg/kg SX-3228, sc, to rats 1 h after the beginning of the light phase of the light-dark cycle induced a significant reduction of rapid-eye-movement sleep (REMS) during the third recording hour. Moreover, slow wave sleep (SWS) was increased during the fourth recording hour after the two largest doses of the compound. Administration of 0.5, 1.0 and 2.5 mg/kg SX-3228 one hour after the beginning of the dark period of the light-dark cycle caused a significant and maintained (6-h recording period) reduction of waking (W), whereas SWS and light sleep (LS) were increased. REMS values tended to... Tipo: Info:eu-repo/semantics/article Palavras-chave: SX-3228; Benzodiazepine1 receptor; Sleep; Waking; REM sleep; Zolpidem; Light-dark cycle. Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000800011 Sawtooth waves during REM sleep after administration of haloperidol combined with total sleep deprivation in healthy young subjects BJMBR Pinto Jr.,L.R.; Peres,C.A.; Russo,R.H.; Remesar-Lopez,A.J.; Tufik,S.. We sought to examine the possible participation of dopaminergic receptors in the phasic events that occur during rapid eye movement (REM) sleep, known as sawtooth waves (STW). These phasic phenomena of REM sleep exhibit a unique morphology and, although they represent a characteristic feature of REM sleep, little is known about the mechanisms which generate them and which are apparently different from rapid eye movements. STW behavior was studied in 10 male volunteers aged 20 to 35 years, who were submitted to polysomnographic monitoring (PSG). On the adaptation night they were submitted to the first PSG and on the second night, to the basal PSG. On the third night the volunteers received placebo or haloperidol and spent the whole night awake. On the... Tipo: Info:eu-repo/semantics/article Palavras-chave: Sawtooth waves; REM sleep; Sleep deprivation; Dopaminergic receptors; Rapid eye movements; Haloperidol. Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000500013 Registros recuperados: 3 Primeira ... 1 ... Última

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