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| Miagostovich,M.P.; Santos,F.B. dos; Simone,T.S. de; Costa,E.V.; Filippis,A.M.B.; Schatzmayr,H.G.; Nogueira,R.M.R.. |
| The genetic characterization of dengue virus type 3 (DEN-3) strains isolated from autochthonous cases in the State of Rio de Janeiro, Brazil, in 2001 is presented. Restriction site-specific (RSS)-PCR performed on 22 strains classified the Brazilian DEN-3 viruses as subtype C, a subtype that contains viruses from Sri Lanka, India, Africa and recent isolates from Central America. Nucleic acid sequencing (positions 278 to 2550) of one DEN-3 strain confirmed the origin of these strains, since genotype III - classified by sequencing - and RSS-PCR subtype C are correlated. This genetic subtype has been associated with hemorrhagic dengue epidemics and the information provided here could be useful to implement appropriate prevention and control measures. |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Dengue viruses type 3; Sequencing; RSS-PCR; Rio de Janeiro; Brazil. |
| Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000800002 |
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