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	Provedor de dados Biol. Res. (1) BJMBR (1) Autor Andreatta-Van Leyen,S. (1) Araujo,G.C. (1) Campos,R.R. (1) Chianca-Jr,Deoclecio Alves (1) Gonçalves Fernandes,Luciano (1) Guertzenstein,P.G. (1) Lacerda,J.E.C. (1) Lopes,O.U. (1) Rodrigues,Fabiana Aparecida (1) Mais... Palavra-chave RVLM (2) Baroreflex (1) Blood pressure (1) Conscious rats (1) GABA (1) Heart rate (1) L-glutamate receptors (1) Malnutrition (1) Vasomotor tone (1) Ventrolateral medulla (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Journal article (1) Ano 2012 (1) 2003 (1) País Brazil (1) Chile (1) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Malnutrition affects the pressor response to microinjection of L-glutamate into the RVLM of awake rats Biol. Res. Rodrigues,Fabiana Aparecida; Chianca-Jr,Deoclecio Alves; Gonçalves Fernandes,Luciano. Post-weaning protein malnutrition is often related to the development of cardiovascular and metabolic diseases in humans, as well to changed content of neurotransmitters in the central nervous system under experimental conditions. The rostral ventrolateral medulla (RVLM) is a bulbar region that contains sympathetic premotor neurons; the excitatory amino acid L-glutamate seems to be the main neurotransmitter at this level. The aim of the present study was to evaluate the possible change in the L-glutamate sensitivity of the RVLM neurons of malnourished animals. Male Fischer rats were divided into two groups: control (n = 15) and malnourished (n = 19). Four days before the experiments, guide cannulas were implanted bilaterally in direction of the RVLM for... Tipo: Journal article Palavras-chave: Baroreflex; Blood pressure; L-glutamate receptors; Heart rate; Malnutrition; RVLM. Ano: 2012 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000400002 Cardiovascular responses to microinjections of GABA or anesthetics into the rostral ventrolateral medulla of conscious and anesthetized rats BJMBR Lacerda,J.E.C.; Campos,R.R.; Araujo,G.C.; Andreatta-Van Leyen,S.; Lopes,O.U.; Guertzenstein,P.G.. The rostral ventrolateral medulla (RVLM) contains neurons involved in tonic and reflex control of arterial pressure. We describe the effects of gamma-aminobutyric acid (GABA) and anesthetics injected into the RVLM of conscious and urethane (1.2 g/kg, iv) anesthetized Wistar rats (300-350 g). In conscious rats, bilateral microinjection of GABA (50 nmol/200 nl) induced a small but significant decrease in blood pressure (from 130 ± 3.6 to 110 ± 5.6 mmHg, N = 7). A similar response was observed with sodium pentobarbital microinjection (24 nmol/200 nl). However, in the same animals, the fall in blood pressure induced by GABA (from 121 ± 8.9 to 76 ± 8.8 mmHg, N = 7) or pentobarbital (from 118 ± 4.5 to 57 ± 11.3 mmHg, N = 6) was significantly increased after... Tipo: Info:eu-repo/semantics/article Palavras-chave: Vasomotor tone; Ventrolateral medulla; RVLM; GABA; Conscious rats. Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000900019 Registros recuperados: 2 Primeira ... 1 ... Última

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