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Transcolonic Perirectal NOTES Access (PNA): A feasibility study with survival in swine model Anais da ABC (AABC)
OLIVEIRA,ANDRÉ L.A.; ZORRON,RICARDO; OLIVEIRA,FLAVIO M.M. DE; SANTOS JUNIOR,MARCELO B. DOS; SCHEFFER,JUSSARA P.; RIOS,MARCELO; ANTUNES,FERNANDA.
ABSTRACT Transrectal access still has some unsolved issues such as spatial orientation, infection, access and site closure. This study presents a simple technique to perform transcolonic access with survival in a swine model series. A new technique for NOTES perirectal access to perform retroperitoneoscopy, peritoneoscopy, liver and lymphnode biopsies was performed in 6 pigs, using Totally NOTES technique. The specimens were extracted transanally. The flexible endoscope was inserted through a posterior transmural incision and the retrorectal space. Cultures of bacteria were documented for the retroperitoneal space and intra abdominal cavity after 14 days. Rectal site was closed using non-absorbable sutures. There was no bowel cleansing, nor preoperative...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Rectal cancer; Total mesorectal excision; Colorectal surgery; Natural orifice surgery; Minimally invasive surgery.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000200685
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Changes in NAD/ADP-ribose metabolism in rectal cancer BJMBR
Yalcintepe,L.; Turker-Sener,L.; Sener,A.; Yetkin,G.; Tiryaki,D.; Bermek,E..
The extent of ADP-ribosylation in rectal cancer was compared to that of the corresponding normal rectal tissue. Twenty rectal tissue fragments were collected during surgery from patients diagnosed as having rectal cancer on the basis of pathology results. The levels of ADP-ribosylation in rectum cancer tissue samples (95.9 ± 22.1 nmol/ml) was significantly higher than in normal tissues (11.4 ± 4 nmol/ml). The level of NAD+ glycohydrolase and ADP-ribosyl cyclase activities in rectal cancer and normal tissue samples were measured. Cancer tissues had significantly higher NAD+ glycohydrolase and ADP-ribosyl cyclase activities than the control tissues (43.3 ± 9.1 vs 29.2 ± 5.2 and 6.2 ± 1.6 vs 1.6 ± 0.4 nmol mg-1 min-1). Approximately 75% of the NAD+...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Rectal cancer; ADP-ribosylation; NAD+; NAD+ glycohydrolase; Poly(ADP-ribose) polymerase.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000300006
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