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	Provedor de dados BJMBR (1) Autor Borges,M.C. (1) Ferraz,E. (1) Terra-Filho,J. (1) Vianna,E.O. (1) Palavra-chave Bronchial challenge (1) Bronchial provocation test (1) Hypertonic saline (1) Refractory period (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2008 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Protective effect of bronchial challenge with hypertonic saline on nocturnal asthma BJMBR Borges,M.C.; Ferraz,E.; Terra-Filho,J.; Vianna,E.O.. Inhalation of hypertonic saline (HS) causes bronchoconstriction in asthmatic subjects. Repeated inhalation of HS leads to substantially reduced bronchoconstriction, known as the refractory period. Refractoriness due to different stimuli has also been described (cross-refractoriness). Nocturnal asthma is defined as an increase in symptoms, need for medication, airway responsiveness, and/or worsening of lung function that usually occurs from 4 to 6 am. Our objective was to determine the effect of refractoriness on nocturnal asthma. The challenge test consisted of inhalations of 4.5% saline with increasing durations until a reduction of 20% in forced expiratory volume in 1 s (FEV1) (PD20HS) or total time of 15.5 min. Twelve subjects with nocturnal asthma were... Tipo: Info:eu-repo/semantics/article Palavras-chave: Refractory period; Bronchial challenge; Hypertonic saline; Bronchial provocation test. Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000300006 Registros recuperados: 1 Primeira ... 1 ... Última

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