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Are the current chronic allograft nephropathy grading systems sufficient to predict renal allograft survival? BJMBR
Moscoso-Solorzano,G.T.; Mastroianni-Kirsztajn,G.; Ozaki,K.S.; Araujo,S.; Franco,M.F.; Pacheco-Silva,A.; Camara,N.O.S..
A major problem in renal transplantation is identifying a grading system that can predict long-term graft survival. The present study determined the extent to which the two existing grading systems (Banff 97 and chronic allograft damage index, CADI) correlate with each other and with graft loss. A total of 161 transplant patient biopsies with chronic allograft nephropathy (CAN) were studied. The samples were coded and evaluated blindly by two pathologists using the two grading systems. Logistic regression analyses were used to evaluate the best predictor index for renal allograft loss. Patients with higher Banff 97 and CADI scores had higher rates of graft loss. Moreover, these measures also correlated with worse renal function and higher proteinuria...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Renin angiotensin-converting enzyme inhibitor; Chronic allograft damage index; Banff 97; Renal allograft survival; Kidney transplantation.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008001000011
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