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| Volpato,Gustavo T.; Francia-Farje,Luis A.D.; Damasceno,Débora C.; Oliveira,Renata V.; Hiruma-Lima,Clélia A.; Kempinas,Wilma G.. |
| Citrus aurantium L., commonly known as bitter orange, is widely used in folk medicine, but there is little data in the literature about the effects on pregnancy. The aim of the present study was to evaluate the influence of essential oil obtained from fruits of Citrus aurantium on the maternal reproductive outcome and fetal anomaly incidence in rats. Pregnant Wistar rats were randomized into four groups (n minimum = 12 animals/group): G1 = control, G2 to G4 = treated with essential oil from C. aurantium at dose 125, 250 and 500 mg/kg, respectively. Rats were orally treated, by gavage, with plant essential oil or vehicle during pre-implantation and organogenic period (gestational day 0-14). On gestational day 20 the rats were anaesthetized and the gravid... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Citrus aurantium; Essential oil; Limonene; Malformation; Pregnancy; Reproductive outcome. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652015000100407 |
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| Rudge,M.V.C.; Damasceno,D.C.; Volpato,G.T.; Almeida,F.C.G.; Calderon,I.M.P.; Lemonica,I.P.. |
| The aim of the present study was to evaluate the effect of Ginkgo biloba treatment (EGb 761, 200 mg kg-1 day-1) administered from day 0 to 20 of pregnancy on maternal reproductive performance and on the maternal and fetal liver antioxidant systems of streptozotocin-induced diabetic Wistar rats. On day 21 of pregnancy, the adult rats (weighing approximately 250 ± 50 g, minimum number = 13/group) were anesthetized to obtain maternal and fetal liver samples for superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), and total glutathione (GSH-t) determinations. The uterus was weighed with its contents. The diabetic (G3) and treated diabetic (G4) groups of rats presented significant maternal hyperglycemia, reduced term pregnancy rate,... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Ginkgo biloba; Diabetes mellitus; Pregnancy; Reproductive outcome; Oxidative stress. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000800010 |
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