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| Registros recuperados: 89 | |
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| COSTA-SILVA,DANYLO R.; BARROS-OLIVEIRA,MARIA DA CONCEIÇÃO; BORGES,RAFAEL S.; TAVARES,CLÉCITON B.; BORGES,UMBELINA S.; ALVES-RIBEIRO,FRANCISCO A.; SILVA,VLADIMIR C.; SILVA,BENEDITO B. DA. |
| ABSTRACT Insulin-like Growth Factor-1 (IGF-1) gene polymorphism has been associated with an increased risk for breast cancer. IGF-1 is a key regulator of proliferation, cell differentiation and apoptosis. It has important mitogenic and anti-apoptotic activities in normal cells and in breast cancer cells, acting synergistically with estrogen to increase neoplastic cell proliferation. This review aims to present the recent finds of IGF-1 gene polymorphism and its relationship with the risk of breast cancer through following the polymorphic dinucleotide repeat cytosine-adenine (CA) and single nucleotide polymorphisms (SNPs) by searching in the PubMed database publications focused studies published from 2010 to 2015 related to IGF-1 gene polymorphism and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Breast cancer; Risk factors; IGF-1; IGF-1 gene polymorphism. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000602349 |
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| HERRERA-RIVERO,MARISOL; SOTO-CID,ABRAHAM; HERNáNDEZ,MARíA E.; ARANDA-ABREU,GONZALO E.. |
| Although Alzheimer's disease is a brain disorder, a number of peripheral alterations have been found in these patients; however, little is known about how the key genes involved in the pathophysiology express in peripheral cells such as lymphocytes during normal compared to neuropathological ageing. We analysed the expression of tau, of the amyloid precursor protein, of nicastrin and of the β-site APP cleaving enzyme genes by RT-PCR in lymphocytes from a small group of late-onset Alzheimer's disease patients, from aged patients suffering from neuropsychological conditions different from Alzheimer's and from cognitively healthy subjects divided in four groups by age. We also investigated correlations between gene expression and levels of blood pressure,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Alzheimer's disease; APP; BACE1; Nicastrin; Normal ageing; Risk factors. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000401489 |
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| Moura,A.B; Souza,A.P; Sartor,A.A; Bellato,V; Pisetta,G.M; Teixeira,E.B; Heusser Junior,A. |
| Identificaram-se os fatores de risco e a ocorrência de anticorpos contra Neospora caninum em cães das cidades de Lages e Balneário Camboriú, SC. Amostras de soro de 400 cães domiciliados (200 de cada município) foram processadas para a detecção de anticorpos contra N. caninum pela técnica de imunofluorescência indireta. Informações acerca dos fatores de risco foram obtidas por meio de questionário. Dos 400 cães, 49 (12,3%) apresentaram anticorpos contra N. caninum. Em Lages, 26 (13%) foram positivos para N. caninume; em Balneário Camboriú, 23 (11,5%). Não foram observadas diferenças estatísticas entre as ocorrências de anticorpos contra N. caninum (P= 0,647) nas duas cidades. Das variáveis analisadas, somente idade apresentou associação (P=0.020, odds... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Dog; Neospora caninum; Risk factors; Epidemiology. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352011000100039 |
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| Lopes,E.G.P.; Oviedo-Pastrana,M.E.; Borges,L.F.N.M.; Freitas,A.C.P.; Dias,E.S.; Silva,S.R.; Haddad,J.P.A.; França-Silva,J.C.; Soares,D.F.M.. |
| ABSTRACT Visceral leishmaniasis (VL) has spread rapidly across cities in the metropolitan region of Belo Horizonte. The aim of this study was to investigate VL dynamics in a prospective cohort study of dogs in Juatuba, between 2010 and 2011, to confirm the incidence of Leishmania infantum, and to assess possible risk factors associated with infection. An observational and prospective closed cohort study was performed using serology testing in dogs, randomly selected from the whole municipality. All seronegative dogs, or dogs with inconclusive results were monitored using indirect immunofluorescence (IIF) at 6-month intervals. The dog's owners completed a semi-structured questionnaire to assess possible causal factors of seroconversion, and the responses... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Leishmaniasis; Incidence; Seroconversion; Risk factors; Cluster. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352016000601403 |
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| Macêdo,A.A.M.; Oliveira,J.M.B.; Silva,B.P.; Borges,J.M.; Soares,L.B.F.; Silva,G.M.; Santos,S.B.; Mota,R.A.; Pinheiro-Júnior,J.W.. |
| ABSTRACT The objective of this study was to conduct an investigation of Mycoplasma bovigenitalium and Ureaplasma diversum infections in cattle in the microregion of the Ipanema Valley, state of Pernambuco, Brazil. Vaginal swabs were collected from 355 breeding cows in reproductive age and were analyzed by multiplex PCR (mPCR) and culture. An epidemiological investigation of risk factors was performed for Mollicutes. mPCR analysis showed that, 9.29% (33/355) of the cows were positive for M. bovigenitalium and 21.69% (77/355) for U. diversum; coinfection was observed in 2.81% (10/355) of the cows. The microbiological isolation showed, 81.81% (27/33) of Mycoplasma spp. and 24.67% (19/77) of Ureaplasma spp.. The risk factors related to Mollicutes infection... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: MPCR; Mollicutes; Cows; Risk factors; Ipanema valley. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352018000601798 |
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| Chalghoum,Abdelkader; Noichri,Yosri; Karkouch,Ines; Dandana,Azza; Baudin,Bruno; Jeridi,Guieder; Ferchichi,Salima; Miled,Abdelhédi. |
| BACKGROUND: Acute coronary syndromes (ACS) are complex and polygenic diseases which are a real problem of public health. These syndromes require multidisciplinary studies to understand the pathogenesis mechanisms and metabolic interactions between different risk factors.This study aimed to explore the variation of two coronary risk parameters not mentioned by Framingham cohorts, hyperhomocysteinemia and endothelin-1 (ET-1) in Tunisian coronary and the study of the variation of these parameters based on various cardiac risk factors and metabolic relationship between them.To 157 coronary and 142 healthy subjects, the concentration of homocysteine was quantified by fluorescence polarization immunoassay; the concentration of ET-1 was measured by an analytical... |
| Tipo: Journal article |
Palavras-chave: Acute coronary syndrome; Endothelin-1; Hyperhomocysteinemia; Risk factors. |
| Ano: 2015 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100032 |
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| Rodrigues,Maria N.; Queiroz,Dulciene M. M.; Rodrigues,Rodrigo T.; Rocha,Andreia M.C.; Braga Neto,Manuel B.; Braga,Lucia L.B.C.. |
| We investigated the prevalence and the risk factors for infection with Helicobacter pylori in a randomly-selected population of adults from a low-income community in Northeastern Brazil. Helicobacter pylori infection was determined by ELISA. Risk factors were assessed using a structured interview. Two hundred and four individuals were included in the study, including 49 males and 155 females, ranging from 18 to 80 years old. Overall, 165 of 204 participants (80%) were H. pylori positive, without significant gender differences (p= 0.49). The infection rate was of 84.7% in subjects 18 to 30 years of age, increasing to 92% in subjects 46-60 years old. Above 60 years old, the prevalence decreased slightly. As a whole, the prevalence of infection did not... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Helicobacter pylori; Prevalence; Risk factors; Northeastern Brazil. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000500008 |
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| Cho,Sung Min; Lee,Jae Joon; Yoon,Hee Jung. |
| Many factors appear to influence the chance of acquiring Clostridium difficile (C. difficile) infection, and an accurate identification of risk factors could be beneficial in many ways. Thus, in the present study, clinical risk factors for C. difficile-associated disease (CDAD) in Korea were identified. A total of 93 patients who met the inclusion criteria and 186 age/gender/ward/admission period-matched control patients were included in this study. Statistically significant associations were found with presence of chronic lung diseases (odds ratio [OR], 3.41; 95% confidence interval [CI], 1.25-9.32; p = 0.017), presence of ileus (OR, 10.05; 95% CI, 2.42-41.80; p = 0.001), presence of intensive care unit (ICU) stay (OR, 9.79; 95% CI, 3.03-31.68; p <... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Risk factors; Clostridium difficile-associated; Diseases. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000300007 |
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| Silva,Tânia Maria Pazin Marques; Ferreto,Lirane Elize Defante; Follador,Franciele Ani Caovilla; Vieira,Ana Paula; Yamada,Roberto Shigueyasu; Lucio,Léia Carolina; Titon,Joana Perotta; Torres,Renata Himovski; Amaral,Greicy Cézar do; Coelho,Harnoldo Colares. |
| ABSTRACT Background: The prison system in Paraná, Brazil, is experiencing serious problems related to the increasing number of prisoners. Control of hepatitis C virus (HCV) has become more intense because the incarcerated population is considered a high-risk group for contagious diseases due to the favorable conditions found in prisons for the spread of these morbidities. The objective of this study was to identify features associated with hepatitis C infection among male prisoners in correctional institutions of Paraná state, Brazil. Methods: This was a case-control study (27 cases and 54 controls) of men incarcerated in 11 penitentiaries in Paraná, Brazil. Information was obtained through a questionnaire in a cross-sectional epidemiological survey on... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hepatitis C; Risk factors; Prisoners. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702019000300173 |
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| The elderly population will grow rapidly over the next 25 years, however there is little information about hospital infections in this group of patients in Brazil. We examined the prevalence of nosocomial and community infections in elderly (>65 years) patients and their relationship with intrinsic and extrinsic risk factors in a Brazilian University Hospital. A total of 155 hospitalized elderly patients were evaluated, and clinical and demographic information about each patient was obtained from hospital records. The rates of nosocomial and community infections were 16.1% and 25.6%, respectively. When the elderly group with and without nosocomial infections was analyzed, practically all the risk factors considered (use of antibiotics, invasive devices,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Elderly; Nosocomial infections; Risk factors; Brazilian hospitals; Infection control. |
| Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000300006 |
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| Carvalho,Bráulio Matias de; Monteiro,André Jalles; Pires Neto,Roberto da Justa; Grangeiro,Thalles Barbosa; Frota,Cristiane Cunha. |
| Infection with both Human Immunodeficiency Virus (HIV) and Mycobacterium tuberculosis is currently the world's leading cause of death due to infectious agents. We evaluated factors related to the development of tuberculosis (TB) in HIV-infected patients who were being treated at an infectious diseases hospital in Fortaleza, Ceará, Brazil. From January 2004 to December 2005, we made an epidemiological study through the analysis of the medical records of 171 patients, who were diagnosed as having both HIV and tuberculosis. Among these co-infected patients, most (81%, p=0.0006) were male. Co-infection was more frequent (87.8%) among patients over 40 years of age and those with lower educational levels (less than eight years of schooling). Forty-one percent of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HIV; Mycobacterium tuberculosis; HIV/TB co-infection; Risk factors; AIDS. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000400005 |
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| Zirpoli,Josefina Cláudia; Lacerda,Heloisa Ramos; Albuquerque,Valéria Maria Gonçalves de; Albuquerque,Maria de Fátima Pessoa Militão de; Miranda Filho,Demócrito de Barros; Monteiro,Verônica Soares; Barros,Isly Lucena de; Arruda Junior,Evanízio Roque de; Montarroyos,Ulisses Ramos; Ximenes,Ricardo Arraes de Alencar. |
| INTRODUCTION: The incidence of ischemic heart disease is higher in patients with HIV/AIDS. However, the frequency of angina pectoris in these patients is still not known. Literature about this subject is still scarce. OBJECTIVE: To evaluate the prevalence of angina pectoris and risk factors for coronary disease and to examine the association between traditional risk factors and HIV-related risk factors and angina pectoris. METHOD: An epidemiological cross-sectional study, analyzed as case-control study, involving 584 patients with HIV/AIDS. Angina pectoris was identified by Rose questionnaire, classified as definite or possible. Information regarding risk factors was obtained through a questionnaire, biochemical laboratory tests, medical records and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Acquired immunodeficiency; Syndrome; Angina pectoris; Coronary disease; Risk factors. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000100001 |
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| Ramos,Taciana Rabelo Ramalho; Pinheiro Junior,José Wilton; Moura Sobrinho,Pedro Alves de; Santana,Vânia Lúcia de Assis; Guerra,Neurisvan Ramos; Melo,Lúcio Esmeraldo Honório de; Mota,Rinaldo Aparecido. |
| The aim of this paper was to study some epidemiological aspects of the infection by Brucella abortus in risk occupational groups in the microregion of Araguaína, Tocantins. For antibody research, 645 serum samples were analyzed by the complement fixation test (CF). A 4.0% frequency was found (26/645) in patients' serum and among those 4.1% (23/551) were slaughterhouses employees and 8.1% (3/37) rural workers. Of the total positive samples, three (2.0%) were women and 23 (4.7%) men; ten (2.9%) were between the ages of 18 and 30, six (3.4%) between 31 and 40, and nine (8.0%) were above 41 years of age. Risk factors for brucellosis in the study groups were age, background (OR = 2.45; CI 95% = 0.98 to 6.10) and previous work conducted with production animals... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Brucellosis; Epidemiology; Humans; Risk factors. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000200007 |
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| Silva,Giovanni Faria; Nishimura,Nancy F.; Coelho,Kunie Iabuki Rabello; Soares,Elza Cotrim. |
| Progression of chronic hepatitis C is known to be associated with some factors, but influence of HCV genotypes is still controversial. Association between HCV genotypes and other risk factors was examined to determine which factors are associated with progression of infection. One hundred consecutive anti-HCV positive volunteer blood donors were evaluated for several risk factors, examined for HCV genotypes, and submitted to hepatic biopsy and biochemical exams.HCV genotyping were carried out in 89 patients and hepatic biopsy in 78. Transmission routes were found to be illicit intravenous drug use (26%), Gluconergan® use in a non-safe manner (48%) and blood transfusion (15%). HCV genotype was 1 in 45%, 3 in 40%, and it was not associated with the stage of... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hepatitis C; Fibrosis; Risk factors. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000200004 |
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| Registros recuperados: 89 | |
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