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Characterization of new recombinant noroviruses ArchiMer
Ambert Balay, K; Bon, F; Le Guyader, Soizick; Pothier, P; Kohli, E.
Noroviruses are important etiologic agents of acute gastroenteritis and show great genetic diversity. To characterize more fully previously detected strains that could not be assigned unequivocally to one particular genotype based on the RNA polymerase, we have sequenced a region in the capsid gene and, in some cases, in the junction between open reading frame 1 (ORF1) and ORF2. The results allowed us to identify several recombinant noroviruses: GGHb viruses were detected for the first time in France in August 2000 and then spread through France and to Europe during the following winter. Here we present the characterization of three other probable GII recombinants which showed different phylogenetic positions depending on their ORF1 and ORF2 sequences....
Tipo: Text Palavras-chave: Genogroup; RNA recombination; Gastroenteritis; Round structured virus; Reverse transcription; Norovirus.
Ano: 2005 URL: http://archimer.ifremer.fr/doc/2005/publication-1234.pdf
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