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| MOREIRA,DAVYSON L.; SOUZA,PATRÍCIA O.; KAPLAN,MARIA AUXILIADORA C.; PEREIRA,NUNO A.; CARDOSO,GERALDO L.; GUIMARÃES,ELSIE F.. |
| The essential oil from Piper solmsianum leaves and its major compound (sarisan) were tested to verify their influences upon mice behaviour. The essential oil was obtained by hydrodistillation in a modified Clevenger extractor and analysed by GC/ MS. This analysis revealed in the oil the presence of monoterpenes, sesquiterpenes and of arylpropanoids. The compound sarisan, a myristicin analogue, was isolated from the oil to perform the pharmacological tests. Emulsions of the oil and of sarisan (5.0 and 10.0% v/v) were used in the tests. Pentobarbital (30 mg/ kg s.c.) or diazepam (2.5 mg/ kg s.c.) were tested as standard drugs to verify depressant or anxiolytic effects, respectively. Both essential oil and sarisan showed to have exciting and depressant... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Piperaceae; Piper solmsianum; Essential oil; Sarisan; Psychopharmacologic effect. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652001000100004 |
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