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	Provedor de dados OAK (1) Biol. Res. (1) Autor Haneda, Masakazu (1) Nakamura, Kimihide (1) Okada, Mitsuyoshi (1) RIGOTTI,ATTILIO (1) Saito, Ako (1) Yokohama, Shiro (1) Yoneda, Masashi (1) 中村, 公英 (1) Mais... Palavra-chave Scavenger receptor (2) Atherosclerosis (1) Cholesterol metabolism (1) Concanavalin A (1) Cytokine (1) Fucoidan (1) Kupffer cell (1) Lipoprotein (1) Liver injury (1) Selective cholesterol uptake (1) Mais... Tipo do documento Journal article (1) Ano 2006 (1) 2000 (1) País Chile (1) Japan (1) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Fucoidan prevents concanavalin A-induced liver injury through induction of endogenous IL-10 in mice OAK Saito, Ako; Yoneda, Masashi; Yokohama, Shiro; Okada, Mitsuyoshi; Haneda, Masakazu; Nakamura, Kimihide; 中村, 公英. Fucoidan is a complex of sulfated polysaccharides derived from non-mammalian origin such as marine brown algae and induces cytokine expression. We investigated the effect of fucoidan on concanavalin A (Con A)-induced liver injury in mice. Liver injury was induced by an intravenous injection of Con A (18.5 mg/kg). Various doses of fucoidan (1-30 mg/kg) were intravenously administered 30 min before Con A injection. The plasma alanine aminotransferase (ALT) and several cytokines levels were determined, and hepatic histological changes were also assessed. The effect of fucoidan administration by itself on induction of interleukin (IL)-10 in plasma and liver tissue was investigated. Con A administration induced an elevation of plasma ALT level, and fucoidan... Palavras-chave: Concanavalin A; Fucoidan; Liver injury; Cytokine; Kupffer cell; Scavenger receptor. Ano: 2006 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/66 Scavenger Receptors and Atherosclerosis Biol. Res. RIGOTTI,ATTILIO. Scavenger receptors were discovered as cell surface proteins capable of binding and internalization of modified lipoproteins. These receptors exhibit a broad ligand binding specificity including potential physiological and pathophysiological ligands other than modified lipoproteins. Different classes of scavenger receptors have been identified, and their relevance in normal and pathological conditions is under investigation. Recent in vitro and in vivo studies strongly support the role of class A and class B scavenger receptors in lipid transport atherogenesis Tipo: Journal article Palavras-chave: Atherosclerosis; Cholesterol metabolism; Lipoprotein; Scavenger receptor; Selective cholesterol uptake. Ano: 2000 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602000000200009 Registros recuperados: 2 Primeira ... 1 ... Última

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