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Electron Microscopic Evaluation of the Secretory Mechanisms of Renin from Juxtaglomerular Cells International Journal of Morphology
Aktas,Ranan Gulhan; Karabay,Gulten; Taskinalp,Oguz; Kutlu,A. Kemal.
Although the structure and the functions of juxtaglomerular cells (JG) have been well defined, there is still a controversy about the secretory mechanisms of renin from these cells. It has been assumed that exocytosis is the main secretory mechanism in these cells in many studies, while others suggest that secretion occurs in a quite different way in these cells. There are several studies suggesting that diacrine secretion, which is very difficult to visualize, might be the other mechanism for secretion of renin. This study is an attempt to find the answers of these questions by identifying the fine structural features of the secretory granules in juxtaglomerular cells. Cyclosporin A (CyA) has been used in the current experimental study since it has...
Tipo: Journal article Palavras-chave: Juxtaglomerular cells; Secretory granules; Microscopy.
Ano: 2010 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000300011
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