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| Santos,Terezinha de Jesus Teixeira; Costa,Carlos Maurício de Castro; Goubau,Patrick; Vandamme,Anne-Mieke; Desmyter,Jan; Van Dooren,Sonia; Mota,Rosa M. S.; Costa,Francine Bovy de Castro; Oliveira,Ana C. S.; Gomes,Vânia Barreto A.F.; Carneiro-Proietti,Anna B.; Bruin,Veralice Meireles Sales de; Sousa,Francisca C. F. de; Oriá,Reinaldo Barreto. |
| How to handle Western blot (WB) seroindeterminate individuals for Human T-lymphotropic Virus 1/2 (HTLV-1/2) constitutes a challenge for blood banks and fam ilies. We made a cross-sectional study of 191 enzyme linked immunoassay (EIA) reactive individuals from the hematological center (HEMOCE) of Fortaleza (Brazil), examining their serological (WB) and molecular (PCR) diagnosis, and demographic profiles, as well as a possible association of their condition with other infectious pathologies and risk factors. Ethical institutional approval and personal consent were obtained. Out of 191 EIA reactive individuals, 118 were WB seroindeterminate and 73 were seropositive for HTLV-1/2. In the PCR analysis of 41 WB seroindeterminate individuals, 9 (22%) were positive... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Epidemiology; PCR; HTLV-1/2; Seroindeterminate individuals; Hepatitis; Syphilis; Blood transfusion. |
| Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000300005 |
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| Anyanwu,Nneoma Confidence JeanStephanie; Ella,Elijah Ekah; Ohwofasa,Aghogho; Aminu,Maryam. |
| ABSTRACT Human T-lymphotropic viruses (HTLV) are Deltaretroviruses that infect millions of individuals worldwide via the same transmission routes as HIV. With the aim of exposing the possible re-emergence of HTLV in West Africa since discovery, a systematic review was carried out, focusing on the distribution of the virus types and significance of frequent indeterminate reports, while highlighting the need for mandatory routine blood screening. Capturing relevant data from discovery till date, sources searched were Google Scholar, CrossRef, NCBI (PubMed), MEDLINE, Research Gate, Mendeley, abstracts of Conferences and Proceedings, organization websites and reference lists of selected papers. A total of 2626 references were initially retrieved using search... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: HTLV in West Africa; Worldwide distribution; Epidemiology; HAM/TSP; Seroindeterminate individuals; Blood transfusion; ATLL. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702018000300224 |
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