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Ventilation distribution as a contributor to the functional exercise capacity in patients with systemic sclerosis-associated interstitial lung disease without pulmonary hypertension BJMBR
Andrade,F.M.; Oliveira,A.D.; Lopes,A.J..
Phenotypic differences have been described between patients with systemic sclerosis (SSc)-associated interstitial lung disease (ILD) and SSc-associated pulmonary hypertension, including performance differences in the 6-min walk test (6MWT). Moreover, the correlations between the 6MWT and traditional pulmonary function tests (PFTs) are weak, indicating the need to search for new parameters that explain exercise performance. Thus, our objective was to evaluate the impact of ventilation distribution heterogeneity assessed by the nitrogen single-breath washout (N2SBW) test and peripheral muscle dysfunction on the exercise capacity in patients with SSc-ILD and limited involvement of the pulmonary parenchyma. In this cross-sectional study, 20 women with SSc-ILD...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Systemic sclerosis; Respiratory function tests; Ventilation; Nitrogen single-breath washout test; Exercise; Six-minute walk test.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000800601
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Diastolic function is associated with quality of life and exercise capacity in stable heart failure patients with reduced ejection fraction BJMBR
Bussoni,M.F.; Guirado,G.N.; Roscani,M.G.; Polegato,B.F.; Matsubara,L.S.; Bazan,S.G.Z.; Matsubara,B.B..
Exercise capacity and quality of life (QOL) are important outcome predictors in patients with systolic heart failure (HF), independent of left ventricular (LV) ejection fraction (LVEF). LV diastolic function has been shown to be a better predictor of aerobic exercise capacity in patients with systolic dysfunction and a New York Heart Association (NYHA) classification ≥II. We hypothesized that the currently used index of diastolic function E/e' is associated with exercise capacity and QOL, even in optimally treated HF patients with reduced LVEF. This prospective study included 44 consecutive patients aged 55±11 years (27 men and 17 women), with LVEF<0.50 and NYHA functional class I-III, receiving optimal pharmacological treatment and in a stable clinical...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Echocardiography; Left ventricular dysfunction; Six-minute walk test; Dyspnea.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000900803
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