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JAIMOVICH,ENRIQUE; ESPINOSA,ALEJANDRA. |
We studied the effect of IGF-I, insulin and testosterone on intracellular Ca2+ in cultured muscle cells. Insulin produced a fast (<1 s) and transient [Ca2+] increase lasting less than 10 s. IGF-I induced a transient [Ca2+] increase, reaching a fluorescence peak 6 s after stimulus, to return to basal values after 60 s. Testosterone induced delayed (35 s) and long lasting (100-200 s) signals, frequently associated with oscillations. IGF-I, testosterone and electrical stimulation-induced Ca2+ signals were shown to be dependent on IP3 production. All of these Ca2+ signals were blocked by inhibitors of the IP3 pathway. On the other hand, insulin-induced Ca2+ increase was dependent on ryanodine receptors and blocked by either nifedipine or ryanodine. The... |
Tipo: Journal article |
Palavras-chave: Skeletal; Transcription factors; Insulin; IGF-I; Testosterone. |
Ano: 2004 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000400018 |
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Guerra,Danilo Ribeiro; Reis,Francisco Prado; Bastos,Afrânio de Andrade; Brito,Ciro José; Silva,Roberto Jerônimo dos Santos; Aragão,José Aderval. |
The anatomy of the psoas minor muscle in human beings has frequently been correlated with ethnic and racial characteristics. The present study had the aim of investigating the anatomy of the psoas minor, by observing its occurrence, distal insertion points, relationship with the psoas major muscle and the relationship between its tendon and muscle portions. Twenty-two human fetuses were used (eleven of each gender), fixed in 10% formol solution that had been perfused through the umbilical artery. The psoas minor muscle was found in eight male fetuses: seven bilaterally and one unilaterally, in the right hemicorpus. Five female fetuses presented the psoas minor muscle: three bilaterally and two unilaterally, one in the right and one in the left hemicorpus.... |
Tipo: Journal article |
Palavras-chave: Psoas Muscles; Muscle; Skeletal; Anatomy; Gender Identity. |
Ano: 2012 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000100024 |
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