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| Ribeiro,Mara Fernandes; Oliveira,Felipe Leite de; Souza,Aline Moreira; Machado,Thelma de Barros; Cardoso,Priscilla Farinhas; Patti Sobrinho,Andrea; Nascimento,Angélica Silveira; Souza,Cláudio Maurício Vieira de; Elias,Sabrina Calil. |
| ABSTRACT Background: Accidents caused by spiders of the genus Loxosceles constitute an important public health problem in Brazil. The venom of Loxosceles sp induces dermonecrosis at the bite site and systemic disease in severe cases. Traditional medicine based on plant-derived products has been proven to reduce the local effects of envenomation. The present study verified the healing effects of copaiba oil on lesions induced by the venom of L. intermedia. Methods: Cutaneous lesions were induced on the backs of rabbits by intradermal injection of L. intermedia venom. Copaiba oil was applied topically 6 hours after injection; the treatment was repeated for 30 days, after which animal skins were removed and processed for histopathological analysis. Blood... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Loxosceles intermedia; Venom; Skin lesion; Copaiba oil; Topical treatment. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992019000100310 |
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| Rocha, Denise Alvarenga; Queiroz, Estela de Rezende; Botelho, Lucimara Nazaré Silva; Fráguas, Rodrigo Martins; Santos, Cláudia Mendes dos; Abreu, Celeste Maria Patto; Sousa, Raimundo Vicente de. |
| The pineapple is a fruit that has wide acceptance worldwide both in natural form, as industrialized. Your peel is a residue generated by food industries and from this residue can obtain a protein extract which is a good source of bromelain. This study aimed to obtain a protein extract from pineapple peel, evaluate its enzyme activity and its healing properties in skin lesions in rats. Seven animal groups were used: control, treated with 5% of protein extract, 10% of protein extract and pure protein extract; 5% of commercial bromelain, 10% of commercial bromelain and pure commercial bromelain. The animals were subjected to a tissue incision and treated for 21 days. Proteolytic and specific activities of the protein extract were 1.30 U mg-1 and 45 x 10-3 U... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ciências Biológicas bromelain; Skin lesion; Enzyme activity; Pineapple and healing. Bioquímica. |
| Ano: 2019 |
URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/41466 |
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| Pereira,Washington Luiz Assunção; Costa,Antônio Messias; Imbeloni,Aline Amaral; Figueiredo,Thatiana de Andrade; Silva,Klena Sarges Marruaz da. |
| The objective of this note is to describe a case of exuberant scarring formation, with keloid characteristics and pseudo-tumoral configuration in a male Black caiman (Melanosuchus niger), with an estimated age of 60 years, belonging to the Zoobotanical Park at the Emílio Goeldi Museum, located in Belém, Pará, Brazil. The alteration appeared on the right posterior limb involving two distal phalanges of the lateral digit and measured 12.4cm at the greatest width. The keloid tissue was surgically removed and samples were processed and analyzed histopathologically, revealing growth made up of fibrous connective tissue with the habitual morphology, which was structurally mature in the more central areas. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Skin lesion; Black caiman; Melanosuchus niger; Keloid. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782013000700021 |
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