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| Teixeira,Raquel da Silva; Rocha,Paula Rafaela; Polonini,Hudson Caetano; Brandão,Marcos Antônio Fernandes; Chaves,Maria das Graças Afonso Miranda; Raposo,Nádia Rezende Barbosa. |
| In order to treat hyperpigmentation-related problems, there has been a global trend in developing cosmetics claiming to have skin-whitening properties, which act by inhibiting melanin biosynthesis. The objective of this work was to evaluate the in vitro mushroom tyrosinase inhibitory activity of five Amazonian native flora oils, and so to verify the possibility of their incorporation into cosmetic products. In addition, the fatty acid composition of the essential oils was determined by gas chromatography-flame ionisation detection in order to determine the main components of these oils. The tyrosinase inhibitory activity of the tested oils was found to be in the following order: açaí (IA50 = 66.08 µg mL-1) > tucumã > patauá > pracaxi > castanha... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Amazonian plants/evaluation; Amazonian plants/dermatological use; Skin lightening agents; Tyrosinase/inhibition; Tyrosinase/in vitro evaluation; Melanin; Hyperpigmentation/treatment. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000300006 |
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| Macrini,Daclé Juliani; Suffredini,Ivana Barbosa; Varella,Antonio Drauzio; Younes,Riad Naim; Ohara,Mitsuko Taba. |
| Dermatological disorders related to pigmentation result in tenuous hyper or hypopigmentation Cosmetic and pharmaceutical products containing depigmenting substances are used in the treatment of patients who have high pigmentation disorders, such as melasma or chloasma, post-inflammatory hyperpigmentation, senile lentigo and ephelides. Skin lightening agents are not yet totally effective or safe and therefore intensive research for the discovery of new agents is continuous. Enzyme inhibitors involved in melanogenesis, such as tyrosinase, have been discovered in Asian countries, including those isolated from plant extracts. The Brazilian flora has the highest species diversity in the world, and the chemical, pharmacological and cosmetic potential for the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Tyrosinase; Melanin; Plant extract/in vitro evaluation; Skin lightening agents; Amazonian plants/evaluation/dermatological use. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000400015 |
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