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| MOREIRA,RAQUEL R.D.; MARTINS,GILMARCIO Z.; MAGALHÃES,NATHÁLIA O.; ALMEIDA,ADÉLIA E.; PIETRO,ROSEMEIRE C.L.R.; SILVA,FLÁVIA A. J.; CICARELLI,REGINA M.B.. |
| The present investigation was to evaluate the potential trypanocidal activity of crude ethanolic extract of the fruits of Solanum palinacanthum, Solanum lycocarpum and the glycoalcaloid, solamargine. S. palinacanthum and S. lycocarpum fruit powders were submitted to exhaustively extraction with 96% ethanol and solamargine were isolated from the extract of S. palinacanthum. Both extracts and solamargine were analysed for trypanocidal activity by using MTT colorimetric assay. Extracts of S. palinacanthum showed to be more active (IC50 = 175.9 µg.ml–1) than S. lycocarpum (IC50 = 194.7 µg.ml–1). Solamargine presented a strong activity (IC50 = 15.3 µg.ml–1), which can explain the better activity of the both extracts. Benznidazol (IC50 = 9.0 µg.ml–1) is the only... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Solanum palinacanthum; Solanum lycocarpum; Solamargine; Epimastigote; Antitrypanosomal activity; Trypanosoma cruzi. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000300903 |
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| Pérez-Amador,MC; Muñoz Ocotero,V; García Castañeda,JM; González Esquinca,AR. |
| A comparison was made between plants of Solanum torvum Sw that grow in Chiapas, Mexico, and plants of the same species originating from India. This was effected to establish either similarities or differences between these plants in total alkaloid contents and presence of solasodine, an important alkaloid for the partial synthesis of steroids. The total alkaloid content (0.12%) of the plants coming from Chiapas and India was the same. However, solasodine was found only in the plants of Chiapas. In addition, the total amount of glycoalkaloids (0.038%) and two glycosilated compounds derived from solasodine, solasonine (0.0043%) and solamargine (0.0028%), were determined. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Solanaceae; Solanum torvum; Alkaloids; Solasodine; Solamargine. |
| Ano: 2007 |
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1851-56572007000100004 |
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