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| Luiz,Roberta dos Santos Silva; Suffys,Phillip; Barroso,Elizabeth Clara; Kerr,Ligia Regina Franco Sansigolo; Duarte,Cynthia Romariz; Freitas,Max Victor Carioca; Mota,Rosa Maria Salani; Frota,Cristiane Cunha. |
| OBJECTIVES: This study has used a combination of clinical information, spoligotyping, and georeferencing system to elucidate the genetic diversity of the Mycobacterium tuberculosis isolates circulating in a TB-prevalent municipality of Northeast Brazil. METHODS: A total of 115 M. tuberculosis strains were isolated from pulmonary tuberculosis patients from January 2007 to March 2008 in Fortaleza. Drug susceptibility and spoligotyping assays were performed and place of residence of the patients were georeferenced. RESULTS: Of the M. tuberculosis strains studied, 51 (44.3%) isolates were resistant to at least one drug (R-TB) and 64 (55.7%) were sensitive to all the drugs tested (S-TB). A high frequency of resistance was found in previously treated cases (84%)... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Tuberculosis; Drug-resistant tuberculosis; Georeferencing; Spoligotyping. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000300006 |
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| Higino,Severino Silvano dos Santos; Pinheiro,Sônia Regina; Souza,Gisele Oliveira de; Dib,Cristina Corsi; Rosário,Tatiana Reis do; Melville,Priscilla Anne; Alves,Clebert José; Azevedo,Sérgio Santos de. |
| A total of 8,058 male and female mixed-breed goats and 1-4 years of age were slaughtered over a period of 7 months at the public slaughterhouse of Patos city, Paraíba state, in the Northeast region of Brazil; 822 animals were inspected for gross lesions of tuberculosis, and 12 (1.46%) had lesions suggestive of tuberculosis in the mammary gland, lungs, liver and mediastinal, mesenteric, submandibular, parotid and prescapular lymph nodes. Presence of granulomatous lesions was confirmed in the submandibular lymph node of one (8.3%) goat at the histopathological examination and at the mycobacterium culture the same sample was confirmed positive. Isolate was confirmed as belonging to the M. tuberculosis complex by PCR restriction enzyme analysis (PRA).... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Caprine tuberculosis; Mycobacterium culture; PCR restriction enzyme analysis; Spoligotyping. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000400028 |
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