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Trait anxiety affects the orofacial nociceptive response in rats Biol. Res.
Matos,Anne Caroline C; Teixeira-Silva,Flavia; Goes,Tiago C; Quintans Júnior,Lucindo J; Albuquerque Júnior,Ricardo Luiz C; Bonjardim,Leonardo R.
The aims of the present study were to assess the influence of: a) trait anxiety on orofacial pain; and b) orofacial pain on state anxiety. Forty-four rats were initially exposed to the free-exploratory paradigm for the evaluation of their anxiety profiles. In accordance to the parameter "Percentage of time in the novel side", the animals were considered as presenting high or low levels of trait anxiety when presenting values below the 1st quartile, or above the 3rd quartile, respectively. A week later, formalin-1.5% was injected into the upper lip of each animal. The behavioural nociceptive response, characterized by increased orofacial rubbing (OR), was quantified for 30 minutes, as follows: Total time OR (0-30 minutes: total pain), 1st phase OR (0-6...
Tipo: Journal article Palavras-chave: Trait anxiety; Formalin test; Orofacial nociception; State anxiety.
Ano: 2011 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602011000400007
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