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	Provedor de dados BJPS (3) Infoteca-e (1) Autor Amaral,Maria Helena (2) Almeida,Hugo (1) CARVALHO, C. G. P. (1) CARVALHO, H. W. L. de (1) CARVALHO, L. M. de (1) Conceição,Jaime (1) DRUMOND, M. A. (1) Estanqueiro,Marilene (1) Hernández-León,Alejandra (1) Lara-Hernández,Belem (1) Lobo,José Manuel Sousa (1) Lobão,Paulo (1) MANDARINO, J. M. G. (1) MAZZOLA, L. F. (1) SILVA, M. R. da (1) Villafuerte-Robles,Leopoldo (1) Mais... Palavra-chave Stearic acid (4) Argan oil (1) Cetyl alcohol (1) Dithranol/stability (1) Drugs/release mechanism (1) Excipients (1) Gastric retention (1) Girassol (1) Glyceryl behenate (1) Helianthus Annuus (1) Hydrogenated castor oil (1) Ibuprofen/lipid microparticles (1) Ibuprofen/release profile (1) Ibuprofen/solid dispersions (1) Linoleic acid (1) Matrices hydration (1) Methocel K4M (1) Metronidazole (1) Oleic acid (1) Palmitic acid (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Boletim de Pesquisa e Desenvolvimento (INFOTECA-E) (1) Ano 2019 (1) 2014 (1) 2012 (1) 2009 (1) País Brazil (4) Idioma Inglês (3) Português (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 4 Primeira ... 1 ... Última Qualidade do óleo extraído de aquênios de girassol produzidos na região Nordeste do Brasil. Infoteca-e CARVALHO, C. G. P.; MAZZOLA, L. F.; CARVALHO, L. M. de; CARVALHO, H. W. L. de; MANDARINO, J. M. G.; DRUMOND, M. A.; SILVA, M. R. da. bitstream/item/205742/1/boletim-23.pdf Tipo: Boletim de Pesquisa e Desenvolvimento (INFOTECA-E) Palavras-chave: Helianthus Annuus; Girassol; Ácido Linoléico; Óleo Vegetal; Sunflower oil; Palmitic acid; Linoleic acid; Oleic acid; Stearic acid; Vegetable oil. Ano: 2019 URL: http://www.infoteca.cnptia.embrapa.br/infoteca/handle/doc/1115408 Comparative study of sustained-release lipid microparticles and solid dispersions containing ibuprofen BJPS Almeida,Hugo; Amaral,Maria Helena; Lobão,Paulo. Ibuprofen is one of the most important non-steroidal anti-inflammatory drugs used in the treatment of inflammatory diseases. In its pure state, ibuprofen presents poor physical and mechanical characteristics and its use in solid dosage forms needs the addition of excipients that improve these properties. The selection of the best excipients and the most suitable pharmaceutical dosage form to carry ibuprofen is very important for the industrial success of this drug. Given these factors, lipid microparticles and solid dispersions of ibuprofen with cetyl alcohol, stearic acid, and hydrogenated castor oil were prepared. These formulations were intended to improve the physical and mechanical characteristics and to sustain the release of this drug. Physical... Tipo: Info:eu-repo/semantics/article Palavras-chave: Ibuprofen/solid dispersions; Ibuprofen/release profile; Ibuprofen/lipid microparticles; Ibuprofen/release profile; Excipients; Cetyl alcohol; Stearic acid; Hydrogenated castor oil. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000300020 Use of solid dispersions to increase stability of dithranol in topical formulations BJPS Estanqueiro,Marilene; Conceição,Jaime; Amaral,Maria Helena; Lobo,José Manuel Sousa. The present study was planned to improve the stability of dithranol using solid dispersions (SD). Two different SD at a 1:9 ratio of dithranol/excipient were prepared: one of them using glyceryl behenate as excipient and the other using a mixture of argan oil with stearic acid (1:8 ratio) as excipient. Pure dithranol and SD of dithranol were incorporated in an oil-in-water cream and in a hydrophobic ointment in a drug/dermatological base ratio of 1:10. The physical and mechanical properties of semisolid formulations incorporating the pure drug and the developed SD were evaluated through rheological and textural analysis. To evaluate the stability, L*a*b* color space parameters of SD and semisolid formulations, and pH of hydrophilic formulations were... Tipo: Info:eu-repo/semantics/article Palavras-chave: Dithranol/stability; Topical formulations/development; Solid dispersions/preparation; Stearic acid; Glyceryl behenate; Argan oil. Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502014000300583 Effect of stearic acid on the properties of metronidazole/methocel K4M floating matrices BJPS Lara-Hernández,Belem; Hernández-León,Alejandra; Villafuerte-Robles,Leopoldo. The properties of metronidazole/Methocel K4M sustained release floating tablets have been studied varying the proportion of the lubricant, stearic acid, on formulations with and without sodium bicarbonate. The variables studied include technological properties of the tablets such as tablet hardness and ejection pressure, the drug release profile, the hydration kinetics and the floating behaviour. The presence of stearic acid and sodium bicarbonate improves the floating behaviour for more than 8 hours. The hydration volume, the tablet hardness and the ejection pressure decrease as the stearic acid content increases and the polymer content decreases. Drug dissolution increases with increasing proportions of stearic acid and decreasing proportions of the... Tipo: Info:eu-repo/semantics/article Palavras-chave: Metronidazole; Methocel K4M; Stearic acid; Matrices hydration; Gastric retention; Sodium bicarbonate; Sustained release; Drugs/release mechanism. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502009000300016 Registros recuperados: 4 Primeira ... 1 ... Última

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