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| QUEIROZ,ESTELA R.; ABREU,CELESTE M.P. DE; ROCHA,DENISE A.; SOUSA,RAIMUNDO V. DE; FRÁGUAS,RODRIGO M.; BRAGA,MARIANA A.; CÉSAR,PEDRO H.S.. |
| ABSTRACT Dyslipidemias are associated with the incidence of cardiovascular diseases, obesity, diabetes, hypertension and hepatic steatosis, being the cause of morbidity and mortality. This study investigated the effects of lychee peel flour (PF) on serum levels of total cholesterol (TC), low-density lipoprotein (LDL-c), triacylglycerols (TAG) and various parameters related to obesity, in rats fed a hypercholesterolemic diet. Therefore, 20 male rats were used. In the first 21 days, the animals were fed a hypercholesterolemic diet, except for control group. In the following 21 days, their diets were modified, and they received a standard diet (Control); hypercholesterolemic (Hyper); hypercholesterolemic + 5% PF (PF5) and hypercholesterolemic + 10% PF (PF10).... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cholesterol; Lipid peroxidation; Steatosis; Triacylglycerol; Weight gain. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652018000100267 |
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| MIRANDA,CAROLINA A.; SCHÖNHOLZER,TATIELE E.; KLÖPPEL,EDUARDO; SINZATO,YURI K.; VOLPATO,GUSTAVO T.; DAMASCENO,DÉBORA C.; CAMPOS,KLEBER E.. |
| Abstract Fructose consumption has increased worldwide, and it has been associated with the development of metabolic diseases such as insulin resistance (IR) and steatosis. The aim was to evaluate if lower fructose concentrations may cause pancreatic structural abnormalities, leading to a glucose intolerance without steatosis in male rats. Young male rats orally received 7% fructose solution for 12 weeks. Body weight, food, water, and energy intake were measured. An oral glucose tolerance test (OGTT) was performed. After final experimental period, all rats were anaesthetized and killed. Blood samples were collected for biochemical analyses and organs (liver and pancreas) were processed for morphological analyses. Fructose consumption was not associated with... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Fructose; Glucose intolerance; Islet pancreatic; Steatosis. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000100702 |
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| VIDEIRA,MARCELA; VELASCO,MICHELE; MATOS,PATRÍCIA; CLEMENTE,SÉRGIO C. DE SÃO; SANCHES,OSIMAR; SANTOS,PATRÍCIA; MATOS,EDILSON. |
| A total of 40 specimens of the teleost fish Gobioides grahamae Palmer & Wheeler, 1955 were obtained from the municipality of Salvaterra on Marajó Island in the Brazilian state of Pará. Their livers were removed and processed for light microscopy. Overall, 90% of the specimens presented some degree of steatosis of the liver, which was invariably associated with the presence of Microsporidium sp. The present study confirms the occurrence of steatosis in G. grahamae associated with parasitic infections by Microsporidium. The findings indicate that the condition of otherwise healthy fishes in their natural environment may be affected negatively by parasites. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Marajó Island; Gobioides grahamae; Liver; Steatosis. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652014000301347 |
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| Oliveira,D.C; Costa,L.A.V.S; Lopes,B.F; Lanis,A.B; Borlini,D.C; Maia Júnior,J.A; Costa,F.S. |
| It is reported a case of an eight-year-old Yorkshire Terrier dog, with a history of prolonged use of prednisone in a dosage of 1mg/kg of body weight each 24 hours during two years. The helical computed tomography revealed hepatomegaly associated to a hyperattenuation of the parenchyma, with a radiodensity value of 82.55 Hounsfield units (HU). The spleen presented a mean radiodensity of 57.17HU, and a radiodensity difference of 25.38HU was observed between the two organs. Based on the history and findings of imaging technique, it was determined the presumptive diagnosis of steroidal hepatopathy compatible with accumulation of hepatic glycogen. It was concluded that computed tomography enabled the characterization of hepatic injury and the presumed diagnosis... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dog; Helical computed tomography; Glycogenosis; Steatosis; Prednisone. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352011000100006 |
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| Silva,Andrezza Braga Soares da; Rizzo,Marcia dos Santos; Viloria-Petit,Alicia; Conde Junior,Airton Mendes. |
| Abstract The six-banded armadillo (Euphractus sexcinctus) stands out among wild mammals due to the rare occurrence of spontaneous metabolic diseases. When altered, the liver, which is important in metabolism, may trigger a dysfunctional cascade, leading to hepatic steatosis. Here we describe a case of hepatic steatosis in a six-banded armadillo living in captivity. The female specimen was captured and donated to the Federal University of Piaui under SISBIO authorization nº53303. The animal was first referred for a veterinary clinical evaluation, and then euthanized following the ethical standards of the Federal Council of Veterinary Medicine. At the start of the dissection, the abdominal cavity was accessed and sections of all ex situ liver lobes, spleen... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Euphractus sexcinctus; Infectious; Liver; Six-banded armadillo; Steatosis. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-06032018000100504 |
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| Siqueira,E.R.F.; Oliveira,C.P.M.S.; Correa-Giannella,M.L.; Stefano,J.T.; Cavaleiro,A.M.; Fortes,M.A.H.Z.; Muniz,M.T.C.; Silva,F.S.; Pereira,L.M.M.B.; Carrilho,F.J.. |
| The reduction of hepatic microsomal transfer protein (MTP) activity results in fatty liver, worsening hepatic steatosis and fibrosis in chronic hepatitis C (CHC). The G allele of the MTP gene promoter, -493G/T, has been associated with lower transcriptional activity than the T allele. We investigated this association with metabolic and histological variables in patients with CHC. A total of 174 untreated patients with CHC were genotyped for MTP -493G/T by direct sequencing using PCR. All patients were negative for markers of Wilson’s disease, hemochromatosis and autoimmune diseases and had current and past daily alcohol intake lower than 100 g/week. The sample distribution was in Hardy-Weinberg equilibrium. Among subjects with genotype 1, 56.8% of the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hepatitis C; Steatosis; Fibrosis; Microsomal transfer protein. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000100012 |
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| de Oliveira,E.; Lima,N.S.; Conceição,E.P.S.; Peixoto-Silva,N.; Moura,E.G.; Lisboa,P.C.. |
| Early weaning (EW) leads to overweight, visceral obesity, hyperleptinemia, and insulin resistance in adulthood. Treatment with Ilex paraguariensis (yerba mate) improves obesity and insulin resistance in these animals. Here, we evaluated the effects of chronic treatment with yerba mate on the redox balance and liver morphology of overweight early-weaned rats. To induce EW, we wrapped the dams with bandages to interrupt milk access during the last 3 days of lactation. Control pups (C) had free access to maternal milk for the full 21 days of lactation. On postnatal day (PN) 150, EW offspring were subdivided into the EW+YM group, which received the aqueous extract of yerba mate (1 g/kg bw by gavage once a day for 30 days) and the EW group, which received water... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Early weaning; Programming; Oxidative stress; Steatosis; Liver. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000600619 |
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