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Registros recuperados: 17 | |
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JEFFREYS,Manoel Feitosa; NUNEZ,Cecilia Veronica. |
ABSTRACT The Amazon forest is rich in plant species diversity, among them,Piranhea trifoliata stands out, which is popularly known as piranheira, because their fruits are eaten by fish. Their barks are used as bath composition on uterus inflammation and as tea in malaria treatment. This study aimed to fractionate the dichloromethane and dichloromethane phase from methanolic extract of leaves of Piranhea trifoliata. The leaves were dried, grounded and extracted with dichloromethane, methanol and water. The methanol extract was partitioned with dichloromethane and ethyl acetate. The chromatographic fractionation yielded six pentacyclic triterpenoids: friedelan-3-one, 28-hydroxy-friedelan-3-one, 30-hydroxy-friedelan-3-one, lupeol, α- and β-amyrin mixture,... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Amazon Forest; NMR analysis; Steroids; Terpenes. |
Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672016000200189 |
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ARRIAGA,ANGELA M.C.; MESQUITA,ALDENOR C. DE; POULIQUEN,YVONE B.M.; LIMA,ROBERTO A. DE; CAVALCANTE,SERGIO H.; CARVALHO,MARIO G. DE; SIQUEIRA,JOSÉ A. DE; ALEGRIO,LEILA V.; BRAZ-FILHO,RAIMUNDO. |
From the roots, stems and fruits of Simarouba versicolor (Simaroubaceae) were isolated quassinoids (3, 5-7), triterpenoids (8-14), a mixture of steroids (15-17), the flavonoid kaempferol (18) and the squalene derivative 11,14-diacetoxy-7,10; 15,18-diepoxy-6,19-dihidroxy-6,7,10,11,14,15,18,19-octahydrosqualene (19). Spectral data were used for structural characterization. |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Simarouba versicolor; Simaroubaceae; Quassinoids; Triterpenoids; Steroids; Flavonoid; Squalene derivative. |
Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652002000300004 |
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Vigil,Pilar; Orellana,Renán F; Cortés,Manuel E. |
Spermatozoon acrosome reaction is an exocytotic event of the utmost importance for the development of mammalian fertilisation. Current evidence shows that the triggering of the acrosome reaction (AR) could be regulated by the action of diverse compounds, namely, metabolites, neurotransmitters and hormones. The aim of the present review is to describe the modulating effects of several compounds that have been classified as inductors or inhibitors of acrosome reaction. Among AR inductors, it is necessary to mention progesterone, angiotensin II, atrial natriuretic peptide, cathecolamines, insulin, leptin, relaxin and other hormones. Regarding the inhibitors, oestradiol and epidermal growth factor are among the substances that retard AR. It is worth mentioning... |
Tipo: Journal article |
Palavras-chave: Capacitation; Gamma-aminobutyric acid; Hormone modulation; Steroids; Spermatozoon acrosome reaction. |
Ano: 2011 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602011000200007 |
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Beltrame,Flavio Luis; Pessini,Greisiele Lorena; Doro,Dani Luce; Dias Filho,Benedito Prado; Bazotte,Roberto Barbosa; Cortez,Diógenes Aparício Garcia. |
In this work we investigated the antidiabetic and antibacterial effect of Cissus sicyoides (CS) from Brazil. Diabetic rats that received water (A group) or extracts from the aerial parts of the plant (Cs group) during four weeks were employed. After this period, serum levels of glucose, cholesterol and triglycerides were measured. Glycemia was not affected by treatment with CS. However, there was an increased cholesterol and triglyceride level in Cs group. In addition, bioassay-guided fractionation of methanolic extract from aerial parts of CS was performed for isolation of antibacterial compounds.beta-Sitosterol and sitosterol-beta-D-glucopyranoside isolated showed antibacterial activity against Bacillus subtilis with minimal inhibitory concentrations... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cissus sicyoides; Vitaceae; Experimental diabetes mellitus; Antibiosis; Steroids. |
Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132002000100004 |
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NOGUEIRA,Guilherme de Paula; BARNABE,Renato Campanarut; MOREIRA,Alankardson Ferreira; VERRESCHI,Ieda Terezinha do Nascimento. |
Sexual maturation involves restraint of gonadal activity from birth to puberty, while somatic development continues. Fetal gonadal steroidogenesis is very important for the maintenance of pregnancy and foaling in mares. The present study was conducted to evaluate gonadal steroid serum levels in foals after birth. Five fillies born at Equília Stud Farm, Avaré, SP, Brazil, were studied. Blood samples were collected daily in the morning during the first week of life. Progesterone serum levels were measured by a commercial radioimmunoassay (RIA) kit and estradiol serum levels with a sensitized non-commercial RIA. At birth, both progesterone and estradiol serum levels were high (13.46 ± 5.5 nmol/l and 7.95 ± 1.5 nmol/l) and decreased to undetectable levels at... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Fillies; Steroids; Birth. |
Ano: 2000 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-95962000000400008 |
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Yassin,Mohamed A; El Omri,Halima; Al-Hijji,Ibrahim; Taha,Ruba; Hassan,Reham; Aboudi,Kamal Al; El-Ayoubi,Hanadi. |
Strongyloides stercoralis (S.S.) is a human intestinal parasite, which may lead to complicated strongyloidiasis. We report a case of disseminated strongyloidiasis following the treatment of myeloma. The patient developed skin lesions, respiratory distress, aseptic meningitis and bacterial and fungal sepsis. The diagnosis of strongyloidiasis was established through endotracheal tube secretions. Despite the treatment with Ivermectin and Albendazole, the outcome was fatal. The value of screening for strongyloidiasis is unclear but may be of benefit in patients with hematological malignancies from high endemic areas |
Tipo: Info:eu-repo/semantics/report |
Palavras-chave: Acute respiratory failure; Disseminated strongyloidiasis; Myeloma; Steroids. |
Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702010000500019 |
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Di Pietro,A.; Dayan,G.; Conseil,G.; Steinfels,E.; Krell,T.; Trompier,D.; Baubichon-Cortay,H.; Jault,J.-M.. |
Resistance to chemotherapy in cancer cells is mainly mediated by overexpression of P-glycoprotein (Pgp), a plasma membrane ATP-binding cassette (ABC) transporter which extrudes cytotoxic drugs at the expense of ATP hydrolysis. Pgp consists of two homologous halves each containing a transmembrane domain and a cytosolic nucleotide-binding domain (NBD) which contains two consensus Walker motifs, A and B, involved in ATP binding and hydrolysis. The protein also contains an S signature characteristic of ABC transporters. The molecular mechanism of Pgp-mediated drug transport is not known. Since the transporter has an extraordinarily broad substrate specificity, its cellular function has been described as a "hydrophobic vacuum cleaner". The limited knowledge... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: P-glycoprotein (Pgp); Multidrug resistance; Anticancer chemotherapy; ATP; Steroids; Flavonoids. |
Ano: 1999 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000800001 |
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Schiengold,Marion; Schwantes,Lavínia; Ribeiro,Maria F.; Lothhammer,Nívia; Gonzalez,Tatiana P.; Chies,Jose Artur Bogo; Nardi,Nance B.. |
The multidrug resistance (MDR) phenotype is associated with the expression of P-glycoprotein (Pgp), coded by the multigenic mdr family. Mice present the isoforms mdr1 and mdr3, which are responsible for multidrug resistance, and mdr2, that is involved in the transport of phospholipids. mdr1 expression has more recently been associated also with the secretion of steroid hormones. This work presents an RT-PCR analysis of the expression of mdr isoforms, in several organs of mice during different phases of the estrous cycle. Additionally, females were ovariectomized, submitted to different hormone treatments, and their uterus was analyzed for the expression of mdr isoforms. The results show that in the adrenal gland and ovaries mdr1 is the main isoform during... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Adrenal gland; Multidrug resistance; Ovaries; Steroids; Uterus. |
Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572006000400029 |
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Roberts Jr, D. |
Circannual, diel, and lunal periodic mechanisms in naturally reproducing stocks of tropical and subtropical fishes are reviewed. Manipulations of biological clocks, used to control reproduction in captive broodstocks, are detailed. Experiments to induce controlled maturation and spawning in fishes either test efficacy of changing environmental conditions (regimes), or constant environmental conditions (controlled). Data have been generated in experimental/scientific studies, as well as applied research. Effects of controlled environmental regimes on serum steroids, gametogenesis, spawning, fry performance and egg quality are summarized for selected members of Centropomidae, Serranidae, and Sciaenidae. |
Tipo: Text |
Palavras-chave: Sciaenidae; Serranidae; Centropomidae; Fish culture; Controlled conditions; Sexual maturity; Photoperiods; Fish eggs; Gametogenesis; Steroids; Animal reproductive organs; Brood stocks; Marine fish; Spawning; Sexual reproduction. |
Ano: 1989 |
URL: http://archimer.ifremer.fr/doc/1989/acte-1437.pdf |
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Gourmelon, Michele; Caprais, Marie-paule; Mieszkin, Sophie; Marti, Romain; Wery, Nathalie; Jarde, E.; Derrien, Marc; Jadas-hecart, A.; Communal, P. Y.; Jaffrezic, A.; Pourcher, A. M.. |
The microbiological quality of coastal or river waters can be affected by faecal pollution from human or animal sources. An efficient MST (Microbial Source Tracking) toolbox consisting of several host-specific markers would therefore be valuable for identifying the origin of the faecal pollution in the environment and thus for effective resource management and remediation. In this multidisciplinary study, after having tested some MST markers on faecal samples, we compared a selection of 17 parameters corresponding to chemical (steroid ratios, caffeine, and synthetic compounds), bacterial (host-specific Bacteroidales, Lactobacillus amylovorus and Bifidobacterium adolescentis) and viral (genotypes I-IV of F-specific bacteriophages, FRNAPH) markers on... |
Tipo: Text |
Palavras-chave: Microbial source tracking; Faecal pollution; Bacteroidales; Bifidobacterium adolescentis; Lactobacillus; FRNA bacteriophages; Steroids; Caffeine. |
Ano: 2010 |
URL: http://archimer.ifremer.fr/doc/00016/12710/9690.pdf |
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Maitre, J; Mercier, L; Dolo, L; Valotaire, Y. |
In the liver of rainbow trout (Salmo gairdnerii ), vitellogenin (Vg) synthesis is influenced by oestradiol (E sub(2)) which is believed to act through the classical mechanism of steroid hormone action. After binding of the hormone to a soluble specific receptor protein, the oestradiol-receptor complex is translocated to the nucleus, where it interacts with DNA and modulates expression of Vg genes, leading to increased synthesis of specific mRNA and Vg. The authors show here: (i) the presence of specific oestrogen receptors in the cytosol of the male trout liver. (ii) The male liver, offering, an ideal experimental control of "zero" background, the authors followed - in the liver of male trouts - the kinetics of induction of Vg mRNA by hybridization with Vg... |
Tipo: Text |
Palavras-chave: Salmonidae; Pisces; Proteins; Liver; RNA; Steroids; Biosynthesis; Receptors; Sex hormones; Sexual reproduction. |
Ano: 1983 |
URL: http://archimer.ifremer.fr/doc/1983/acte-1230.pdf |
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Registros recuperados: 17 | |
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