Home Itens selecionados Provedores de dados OAI Créditos Sobre Ajuda

			Busca avançada
	Provedor de dados BJPS (1) Autor Benfica,Polyana Lopes (1) Mota,Mariana Flavia da (1) Valadares,Marize Campos (1) Palavra-chave K-562 cells/apoptosis (1) K-562 cells/cycle arrest (1) Synadenium umbellatum/cytotoxicity (1) Synadenium umbellatum/evaluation (1) Synadenium umbellatum/pharmacognosy (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2012 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Synadenium umbellatum Pax. promotes cell cycle arrest and induces apoptosis in K-562 leukemia cells BJPS Mota,Mariana Flavia da; Benfica,Polyana Lopes; Valadares,Marize Campos. Chronic myeloid leukemia (CML) is a clonal myeloproliferative disease that shows apoptosis resistance. The introduction of imatinib mesylate has revolutionized the treatment of CML, but imatinib resistance may develop at any time and inevitably leads to disease progression. Synadenium umbellatum Pax. belongs to the Euphorbiaceae family and is popularly used in Brazil for the treatment of cancer. The cytotoxicity of Euphorbiaceae is associated with the ability of these plants and their bioactive compounds to induce apoptotic tumor cell death. Therefore, we aimed to investigate the cytotoxicity and the mechanisms of death induced by S. umbellatum extract in leukemic cells. S. umbellatum cytotoxicity was evaluated by trypan blue exclusion assay and flow... Tipo: Info:eu-repo/semantics/article Palavras-chave: Synadenium umbellatum/pharmacognosy; Synadenium umbellatum/cytotoxicity; Synadenium umbellatum/evaluation; K-562 cells/apoptosis; K-562 cells/cycle arrest. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000300017 Registros recuperados: 1 Primeira ... 1 ... Última

Empresa Brasileira de Pesquisa Agropecuária - Embrapa Todos os direitos reservados, conforme Lei n° 9.610 Política de Privacidade Área restrita		Embrapa Parque Estação Biológica - PqEB s/n° Brasília, DF - Brasil - CEP 70770-901 Fone: (61) 3448-4433 - Fax: (61) 3448-4890 / 3448-4891 SAC: https://www.embrapa.br/fale-conosco