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	Provedor de dados BJMBR (1) Autor Leão,R.M. (1) von Gersdorff,H. (1) Palavra-chave Calcium buffer (1) Calyx of Held (1) Capacitance measurements (1) Mammalian auditory brainstem (1) Neurotransmission (1) Synaptic development (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Ano 2009 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Synaptic vesicle pool size, release probability and synaptic depression are sensitive to Ca2+ buffering capacity in the developing rat calyx of Held BJMBR Leão,R.M.; von Gersdorff,H.. The calyx of Held, a specialized synaptic terminal in the medial nucleus of the trapezoid body, undergoes a series of changes during postnatal development that prepares this synapse for reliable high frequency firing. These changes reduce short-term synaptic depression during tetanic stimulation and thereby prevent action potential failures during a stimulus train. We measured presynaptic membrane capacitance changes in calyces from young postnatal day 5-7 (p5-7) or older (p10-12) rat pups to examine the effect of calcium buffer capacity on vesicle pool size and the efficiency of exocytosis. Vesicle pool size was sensitive to the choice and concentration of exogenous Ca2+ buffer, and this sensitivity was much stronger in younger animals. Pool size and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Calyx of Held; Neurotransmission; Calcium buffer; Capacitance measurements; Mammalian auditory brainstem; Synaptic development. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009000100014 Registros recuperados: 1 Primeira ... 1 ... Última

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