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	Provedor de dados OAK (1) BJID (1) Autor Bahari,Gholamreza (1) Eskandari-Nasab,Ebrahim (1) Hashemi,Mohammad (1) Hazire-Yazdi,Leylisadat (1) Ibrahim, H. M. (1) Moazeni-Roodi,Abdolkarim (1) Naderi,Mohammad (1) Nishikawa, Y (1) Taheri,Mohsen (1) Mais... Palavra-chave TLR2 (2) CCR5 (1) Single nucleotide polymorphism (1) TLR11 (1) Toxoplasma gondii (1) Tuberculosis (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Ano 2016 (1) 2013 (1) País Brazil (1) Japan (1) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última The impact of the host CCR5, TLR2 and TLR11 on production of nitric oxide, IL-6, IL-12 and growth of Toxoplasma gondii OAK Ibrahim, H. M.; Nishikawa, Y. The current study investigated the impact of the CCR5, TLR2 and TLR11 on production of nitric oxide (NO), IL-6 and IL-12 and growth of T. gondii, high virulent RH strain and avirulent PLK strain. All examined knockout macrophages infected with PLK strain produced significant lower levels of IL-12. On the other hand, TLR2 and TLR11 macrophages infected with RH strain produced significantly reduced levels of IL-12 as compared to wild-type macrophages. TLR2 and TLR11 macrophages infected with PLK strain significantly inhibited the production of IL-6 when compared to wild-type macrophages. Interestingly, significant reduction in the IL-6 and NO production was observed in TLR2 macrophages infected with PLK strain as compared to wild-type macrophages or to the... Palavras-chave: Toxoplasma gondii; CCR5; TLR2; TLR11. Ano: 2016 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4495 Association between toll-like receptor2 Arg677Trp and 597T/C gene polymorphisms and pulmonary tuberculosis in Zahedan, Southeast Iran BJID Naderi,Mohammad; Hashemi,Mohammad; Hazire-Yazdi,Leylisadat; Taheri,Mohsen; Moazeni-Roodi,Abdolkarim; Eskandari-Nasab,Ebrahim; Bahari,Gholamreza. BACKGROUND: It is well known that toll-like receptor 2 (TLR2) mediates responses of both innate and adaptive immunity to microbial pathogen, including mycobacteria. Single-nucleotide polymorphisms (SNPs) in the TLR2 gene that impair its function may be associated with the development of pulmonary tuberculosis (PTB). The aim of this study was to evaluate the possible association between TLR2 Arg677Trp and 597T/C polymorphisms and PTB in a sample of Iranian population. MATERIALS AND METHODS: This case-;control study was performed on 174 PTB and 177 healthy subjects. Tetra amplification refractory mutation system-polymerase chain reaction (TARMS-PCR) was used to detect the SNPs. RESULTS: There was no significant difference in the polymorphism of Arg677Trp of... Tipo: Info:eu-repo/semantics/article Palavras-chave: Tuberculosis; TLR2; Single nucleotide polymorphism. Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000500002 Registros recuperados: 2 Primeira ... 1 ... Última

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