Home Itens selecionados Provedores de dados OAI Créditos Sobre Ajuda

			Busca avançada
	Provedor de dados BABT (2) Colegio de Postgraduados (1) BJMBR (1) Autor Barrales Cureño, Hebert Jair (1) Cremasco,Marco Aurelio (1) Gong,Weihua (1) Lu,Lu (1) Ren,Jingjing (1) Shi,Ying (1) Starqui,Axel Nicolas (1) Süleymanoglu,Erhan (1) Wang,Yunfeng (1) Mais... Palavra-chave Taxol (4) 10-diacetil baccatina (1) 10-diacetyl baccatin (1) Anticáncer (1) Antineoplastic agents (1) Autophagy (1) Botánica (1) Breast cancer (1) Cancer (1) Cefalomanina (1) Cell viability (1) Cephalomannine (1) Chemotherapy (1) Computer simulation (1) Doctorado (1) Fitohormonas (1) HMGB1 (1) Membrane fluidity (1) MiR-129-5p (1) Multicomponent separation (1) Mais... Tipo do documento Info:eu-repo/semantics/article (3) Ano 2019 (1) 2013 (1) 2010 (2) País Brazil (3) Mexico (1) Idioma Inglês (3) Espanhol (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 4 Primeira ... 1 ... Última Producción de taxoides en cultivos in vitro de callos y células elicitadas de Taxus globosa. Colegio de Postgraduados Barrales Cureño, Hebert Jair. Los objetivos de este trabajo fueron: establecer un método de propagación in vitro para callos y células en suspensión de Taxus globosa, se realizaron pruebas de viabilidad celular; se elicitaron suspensiones celulares con jasmonato de metilo, etanol y una combinación de peróxido de hidrógeno con butionina de sulfoximina. Se cuantificaron tres taxoides: taxol, cefalomanina y 10-diacetil baccatina por Cromatografía Liquida de Alta Resolución en cultivos in vitro de callos, células elicitadas y hojas de T. globosa. La inducción de los callos se originó a los 40 días, el mayor porcentaje se obtuvo con el tratamiento de picloram y polivinil pirrolidona. El análisis por Cromatografía Líquida de hojas de un extracto crudo en metanol registró la mayor acumulación... Palavras-chave: 10-diacetil baccatina; Cefalomanina; Taxol; Anticáncer; Fitohormonas; Viabilidad celular; 10-diacetyl baccatin; Cephalomannine; Phytohormones; Cell viability; Botánica; Doctorado. Ano: 2013 URL: http://hdl.handle.net/10521/2036 Modeling for Taxol® Separation in a simulated moving bed BABT Cremasco,Marco Aurelio; Starqui,Axel Nicolas. This work presents an alternative numerical resolution strategy for a model to describe the dynamic of linear adsorption processes involving multicomponent mixture of taxanes with Taxol® (paclitaxel), a powerful anti-cancer agent, and non-identified impurities, in a Simulated Moving Bed (SMB) system. To solve the model, a hybrid method were used. The liquid concentration inside the particles was found analytically and was related with the liquid bed concentration using Duhamel's theorem. The results from simulation were compared with experimental ones from the literature, showing a good agreement, which demonstrated the applicability of the model and of the hybrid resolution proposed. Tipo: Info:eu-repo/semantics/article Palavras-chave: Cancer; Taxol; Simulated moving bed; Computer simulation; Multicomponent separation. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132010000600020 Thermodynamics of molecular recognitions between antineoplastic drug taxol and phosphatidylcholine BABT Süleymanoglu,Erhan. The aim of this study was to study the basic features of Taxol recognition with phospholipids by applying the thermodynamic and spectroscopic measurements. The obtained information could be used further for deductions on its precise cellular and pharmacological mechanisms of action, on improvements of its solubility properties by phospholipids, as well as for designing the novel lipidic carriers for drug delivery. Tipo: Info:eu-repo/semantics/article Palavras-chave: Antineoplastic agents; Chemotherapy; Taxol; Phoshatidylcholine; Taxol-membrane interactions; Membrane fluidity. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132010000600011 Upregulation of miR-129-5p increases the sensitivity to Taxol through inhibiting HMGB1-mediated cell autophagy in breast cancer MCF-7 cells BJMBR Shi,Ying; Gong,Weihua; Lu,Lu; Wang,Yunfeng; Ren,Jingjing. Although Taxol has improved the survival of cancer patients as a first-line chemotherapeutic agent, an increasing number of patients develop resistance to Taxol after prolonged treatment. The potential mechanisms of cancer cell resistance to Taxol are not completely clear. It has been reported that microRNAs (miRNAs) are involved in regulating the sensitivity of cancer cells to various chemotherapeutic agents. In this study, we aimed to explore the role of miR-129-5p in regulating the sensitivity of breast cancer cells to Taxol. Cell apoptosis and autophagy, and the sensitivity of MCF-7 cells to Taxol were assessed with a series of in vitro assays. Our results showed that the inhibition of autophagy increased the Taxol-induced apoptosis and the sensitivity... Tipo: Info:eu-repo/semantics/article Palavras-chave: MiR-129-5p; HMGB1; Autophagy; Taxol; Breast cancer. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019001100603 Registros recuperados: 4 Primeira ... 1 ... Última

Empresa Brasileira de Pesquisa Agropecuária - Embrapa Todos os direitos reservados, conforme Lei n° 9.610 Política de Privacidade Área restrita		Embrapa Parque Estação Biológica - PqEB s/n° Brasília, DF - Brasil - CEP 70770-901 Fone: (61) 3448-4433 - Fax: (61) 3448-4890 / 3448-4891 SAC: https://www.embrapa.br/fale-conosco