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Micro Hardness of Dental Tissues Influenced by Administration of Aspirin During Pregnancy International Journal of Morphology
Shakila,Nazir; Ali,Ashraf; Zaidi,Shoaib.
The study is associated with the effect of aspirin (Acetyl Salicylic Acid) on the microhardness of mineralized tissues of the offspring's teeth, in response to the ingestion of the drug during pregnancy. Aspirin is a widely used analgesic and antipyretic medicine, for symptomatic treatment. Misuse of this drug during pregnancy may instigate developmental defects in offspring. An experimental control study was designed, in which female rabbits were taken as representative mammalian models and treated with aspirin during pregnancy. Their offspring's teeth were used to assess the microhardness of dental tissues. The rabbits were alienated into two groups, treated and control, consisting of seven rabbits in each set (n= 7). Microhardness was evaluated in three...
Tipo: Journal article Palavras-chave: Dentition; Aspirin; Female rabbits; Teratogenic effect; Microhardness.
Ano: 2015 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000200028
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Effect of Aspirin on the Developing Teeth of Neonates International Journal of Morphology
Nazir,Shakila; Naqvi,Sayed Naeem-ul-Hasan; Ahmed,Masood; Arain,Abdul Hakeem; Nazir,Naema.
The objective of the present study was to evaluate the effect of aspirin (Acetyl Salicylic Acid) on the developing teeth of the fetus while the mothers were treated through out the pregnancy. Aspirin is a widely used analgesic and antipyretic drug used for symptomatic treatment. However, recent animal studies have indicated a potent teratogenicity of Acetyl Salicylic Acid. Its easy availability without prescription has been associated with high possibility of misuse, especially in the developing world. An experimental control study was carried out where female rabbits being treated with aspirin were taken as mammalian model, and their offspring were used to evaluate the developmental defects in teeth. Quantitative analysis of minerals in three types of the...
Tipo: Journal article Palavras-chave: Aspirin; Teratogenic effect; Dentition; Female rabbits.
Ano: 2011 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000100046
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