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Neonatal Administration of Fluoxetine Decreased Final Sertoli Cell Number in Wistar Rats International Journal of Morphology
Silva Junior,Valdemiro Amaro da; Lins Amorim,Marleyne José Afonso Accioly; Amorim Junior,Adelmar Afonso de; Pinto,Catarina Ferreira; Deiró,Tereza B. J.; Oliveira,João Ricardo M. de; Peixoto,Christina Alves; Manhães-de-Castro,Raul.
The aim of the present study was to test the hypothesis that the application of fluoxetine ­ a highly selective serotonin reuptake inhibitor (SSRI) ­ in rats during the suckling period induces changes in testicular development. Groups of newborn male rats were randomly assigned with different doses of fluoxetine 24 hours after birth. Each litter stayed with its respective mother during 21 days. Body weight (BW) was measured daily from the 1st -21st day to calculate daily doses of fluoxetine. 5 mg (T1), 10 mg (T2) 20 mg (T3) or deionized water, were injected intraperitoneally. On the 21st day, animals were heparinized, anesthetized and blood was collected by cardiac puncture to determine by radioimmunoassay the follicle stimulating hormone (FSH) levels....
Tipo: Journal article Palavras-chave: Fluoxetine; Testis development; Sertoli cells; Wistar rats.
Ano: 2008 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000100009
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Opioid system manipulation during testicular development: results on sperm production and sertoli cells population - doi: 10.4025/actascibiolsci.v33i2.5940 Biological Sciences
Cajú, Fernanda Mafra; Universidade Federal Rural de Pernambuco; Queiroz, Gian Carlo D'Angelo; Universidade Federal Rural de Pernambuco; Torres, Sandra Maria; Universidade Federal Rural de Pernambuco; Tenório, Bruno Mendes; Universidade Federal Rural de Pernambuco; Silva Júnior, Valdemiro Amaro; Universidade Federal Rural de Pernambuco.
The Sertoli cell has fundamental importance to the development and maintenance of spermatogenesis, as well as it has a directly proportional numerical relationship to sperm production. The proliferative period of this cell in rats occurs between 13 days pre-natal and 21 days pos-natal, when is established the final population in adult animals. The Leydig cell can modulate the Sertoli cell proliferation during fetal and neonatal period through β-endorphin. The manipulation of opioidergic system can promote changes in parameters related to development of nervous, endocrine and reproductive systems. By the way, the main purpose of this present work was to compare the effects of the blockade of opioid receptor blocking in Sertoli cells using...
Tipo: Estudo histomorfológico Palavras-chave: 2.06.00.00-3; 2.06.03.00-2; 2.07.02.00-0 Naltrexone; Testis development; Spermatogenesis; Wistar rats Morfologia; Histologia; Fisiologia de Órgão e Sistemas Naltrexone; Testis development; Spermatogenesis; Wistar rats.
Ano: 2011 URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/5940
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Histomorphometric analysis of gonads of green turtles (chelonia mydas) stranded on the coast of Espírito Santo state, Brazil Arq. Bras. Med. Vet. Zootec.
Failla,G.; Calais Júnior,A.; Pavanelli,L.; Nunes,L.C..
ABSTRACT Studies on reproduction in sea turtles are important due to its life cycle, migratory patterns, high juvenile mortality and environmental impacts. This study aimed to analyse histomorphometrically gonads of C. mydas from the coastline of the Espírito Santo State, Brazil. Ovaries and testicles were collected between 2014 and 2015 from stranded animals. The material was fixed in formalin 10%, assessed macroscopically and processed for histomorphometrical evaluation. Gonads from 34 individuals were evaluated, twenty-four females and ten males. Macroscopic sexual identification presented 100% accuracy confirmed by histology. Sexual dimorphism was observed in one individual, which was considered as adult (CCL=1.023 m). Microscopy of female gonads...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Follicular development; Testis development; Histology; Ovary; Testicle.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352018000100213
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