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	Provedor de dados Anais da ABC (AABC) (1) Genet. Mol. Biol. (1) Autor Deissler,Helmut (1) Hakomori,Senitiroh (1) Herman,Sandra (1) Sauer,Georg (1) Scholz,Claus-Jürgen (1) Wolfahrt,Sonja (1) Mais... Palavra-chave Tetraspanin (2) CD9 (1) Carbohydrate-binding protein (1) Carbohydrate-to-carbohydrate interaction (1) Clustering (1) Growth factor receptor (1) Integrin (1) Membrane topology (1) Splice variant (1) Transcript (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2013 (1) 2004 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Identification of alternative transcripts of rat CD9 expressed by tumorigenic neural cell lines and in normal tissues Genet. Mol. Biol. Wolfahrt,Sonja; Herman,Sandra; Scholz,Claus-Jürgen; Sauer,Georg; Deissler,Helmut. CD9 is the best-studied member of the tetraspanin family of transmembrane proteins. It is involved in various fundamental cellular processes and its altered expression is a characteristic of malignant cells of different origins. Despite numerous investigations confirming its fundamental role, the heterogeneity of CD9 or other tetraspanin proteins was considered only to be caused by posttranslational modification, rather than alternative splicing. Here we describe the first identification of CD9 transcript variants expressed by cell lines derived from fetal rat brain cells. Variant mRNA-B lacks a potential translation initiation codon in the alternative exon 1 and seems to be characteristic of the tumorigenic BT cell lines. In contrast, variant mRNA-C can... Tipo: Info:eu-repo/semantics/article Palavras-chave: CD9; Tetraspanin; Transcript; Splice variant; Membrane topology. Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572013000200019 Glycosynapses: microdomains controlling carbohydrate-dependent cell adhesion and signaling Anais da ABC (AABC) Hakomori,Senitiroh. The concept of microdomains in plasma membranes was developed over two decades, following observation of polarity of membrane based on clustering of specific membrane components. Microdomains involved in carbohydrate-dependent cell adhesion with concurrent signal transduction that affect cellular phenotype are termed "glycosynapse". Three types of glycosynapse have been distinguished: "type 1" having glycosphingolipid associated with signal transducers (small G-proteins, cSrc, Src family kinases) and proteolipids; "type 2" having O-linked mucin-type glycoprotein associated with Src family kinases; and "type 3" having N-linked integrin receptor complexed with tetraspanin and ganglioside. Different cell types are characterized by presence of specific types... Tipo: Info:eu-repo/semantics/article Palavras-chave: Clustering; Carbohydrate-to-carbohydrate interaction; Carbohydrate-binding protein; Integrin; Tetraspanin; Growth factor receptor. Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652004000300010 Registros recuperados: 2 Primeira ... 1 ... Última

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