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Jabuticaba (Plinia jaboticaba) skin extracts as inhibitors of phospholipases A2 and proteases Anais da ABC (AABC)
MARQUES,TAMARA R.; BRAGA,MARIANA A.; CESAR,PEDRO H.S.; MARCUSSI,SILVANA; CORRÊA,ANGELITA D..
Abstract: The phenolic extracts of jabuticaba skin flour (JSF) were characterized by HPLC, and evaluated for their modulating action upon phospholipases A2 and proteases of snake venom, aiming at their possible use in the treatment of the various diseases associated with the action of venom toxins. Two types of extracts were prepared from JSF: aqueous and methanolic. These extracts, evaluated at different ratios, (venom: extract, m/m), significantly inhibited the phospholipase activity induced by the venom of Bothrops moojeni and Crotalus durissus terrificus, except for Bothrops atrox venom. The greatest hemolysis inhibitory action was observed for the methanolic extract, when incubated with venoms of B. moojeni and C. durissus terrificus, with inhibitions...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Agro-industrial waste; Phenolic compounds; Venom enzymes as laboratory tools; Clotting; Thrombolysis.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300613
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Texture analysis of computed tomography images of acute ischemic stroke patients BJMBR
Oliveira,M.S.; Fernandes,P.T.; Avelar,W.M.; Santos,S.L.M.; Castellano,G.; Li,L.M..
Computed tomography (CT) images are routinely used to assess ischemic brain stroke in the acute phase. They can provide important clues about whether to treat the patient by thrombolysis with tissue plasminogen activator. However, in the acute phase, the lesions may be difficult to detect in the images using standard visual analysis. The objective of the present study was to determine if texture analysis techniques applied to CT images of stroke patients could differentiate between normal tissue and affected areas that usually go unperceived under visual analysis. We performed a pilot study in which texture analysis, based on the gray level co-occurrence matrix, was applied to the CT brain images of 5 patients and of 5 control subjects and the results were...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Texture analysis; Computed tomography; Thrombolysis; Discriminant analysis.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001100012
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Implications of ischemic penumbra for the diagnosis of brain death BJMBR
Coimbra,C.G..
The data reviewed here suggest the possibility that a global reduction of blood supply to the whole brain or solely to the infratentorial structures down to the range of ischemic penumbra for several hours or a few days may lead to misdiagnosis of irreversible brain or brain stem damage in a subset of deeply comatose patients with cephalic areflexia. The following proposals are advanced: 1) the lack of any set of clinically detectable brain functions does not provide a safe diagnosis of brain or brain stem death; 2) apnea testing may induce irreversible brain damage and should be abandoned; 3) moderate hypothermia, antipyresis, prevention of arterial hypotension, and occasionally intra-arterial thrombolysis may contribute to good recovery of a possibly...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ischemic penumbra; Cerebral ischemia; Intracranial pressure; Traumatic brain injury; Brain death; Hypothermia; Thrombolysis; Apnea test.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999001200005
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