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Registros recuperados: 4
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Acute-on-chronic subdural cranial hematoma in a dog: case report Arq. Bras. Med. Vet. Zootec.
Bonelli,M.A.; Silva,I.C.C.; Fernandes,T.H.T.; Schwarz,T.; Costa,F.S..
ABSTRACT A ten-month-old male Yorkshire terrier dog was evaluated via CT four months after traumatic brain injury. The head CT scan showed dilated ventricles associated with a peripheral crescent-shaped collection of blood near the right parietal bone with a mineralized area. The visceral layer of the hematoma was hyperattenuating on the native scan and showed moderate contrast enhancement after administration of intravenous iodinated contrast medium. No fractures were identified in the calvarium. These findings were compatible with acute-on-chronic calcified subdural hematoma, which have been described with more detail in humans. This is the first report to include the description of the imaging findings related to this condition using computed tomography...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Canine; Head trauma; Traumatic brain injury; Computed tomography.
Ano: 2020 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352020000100131
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Implications of ischemic penumbra for the diagnosis of brain death BJMBR
Coimbra,C.G..
The data reviewed here suggest the possibility that a global reduction of blood supply to the whole brain or solely to the infratentorial structures down to the range of ischemic penumbra for several hours or a few days may lead to misdiagnosis of irreversible brain or brain stem damage in a subset of deeply comatose patients with cephalic areflexia. The following proposals are advanced: 1) the lack of any set of clinically detectable brain functions does not provide a safe diagnosis of brain or brain stem death; 2) apnea testing may induce irreversible brain damage and should be abandoned; 3) moderate hypothermia, antipyresis, prevention of arterial hypotension, and occasionally intra-arterial thrombolysis may contribute to good recovery of a possibly...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Ischemic penumbra; Cerebral ischemia; Intracranial pressure; Traumatic brain injury; Brain death; Hypothermia; Thrombolysis; Apnea test.
Ano: 1999 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999001200005
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Possible roles of COX-1 in learning and memory impairment induced by traumatic brain injury in mice BJMBR
Shang,J.L.; Cheng,Q.; Yang,W.F.; Zhang,M.; Cui,Y.; Wang,Y.F..
People who suffer from traumatic brain injury (TBI) often experience cognitive deficits in spatial reference and working memory. The possible roles of cyclooxygenase-1 (COX-1) in learning and memory impairment in mice with TBI are far from well known. Adult mice subjected to TBI were treated with the COX-1 selective inhibitor SC560. Performance in the open field and on the beam walk was then used to assess motor and behavioral function 1, 3, 7, 14, and 21 days following injury. Acquisition of spatial learning and memory retention was assessed using the Morris water maze on day 15 post-TBI. The expressions of COX-1, prostaglandin E2 (PGE2), interleukin (IL)-6, brain-derived neurotrophic factor (BDNF), platelet-derived growth factor BB (PDGF-BB), synapsin-I,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Traumatic brain injury; COX-1; Learning and memory; SC560.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014001201050
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Voluntary exercise prior to traumatic brain injury alters miRNA expression in the injured mouse cerebral cortex BJMBR
Miao,W.; Bao,T.H.; Han,J.H.; Yin,M.; Yan,Y.; Wang,W.W.; Zhu,Y.H..
MicroRNAs (miRNAs) may be important mediators of the profound molecular and cellular changes that occur after traumatic brain injury (TBI). However, the changes and possible roles of miRNAs induced by voluntary exercise prior to TBI are still not known. In this report, the microarray method was used to demonstrate alterations in miRNA expression levels in the cerebral cortex of TBI mice that were pretrained on a running wheel (RW). Voluntary RW exercise prior to TBI: i) significantly decreased the mortality rate and improved the recovery of the righting reflex in TBI mice, and ii) differentially changed the levels of several miRNAs, upregulating some and downregulating others. Furthermore, we revealed global upregulation of miR-21, miR-92a, and miR-874 and...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Voluntary exercise; Running wheel; MiRNA; Traumatic brain injury.
Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000500433
Registros recuperados: 4
Primeira ... 1 ... Última
 

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