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	Provedor de dados Biol. Res. (1) Autor Han,Xu (1) Li,Shuang (1) Ning,Yu (1) Wang,Lingling (1) Wang,Zhenjun (1) Palavra-chave AFAP1-AS1 (1) Colorectal cancer (1) Epithelial-mesenchymal transition (EMT) (1) Tumor metastasis (1) Tipo do documento Journal article (1) Ano 2016 (1) País Chile (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Long non-coding RNA AFAP1-AS1 facilitates tumor growth and promotes metastasis in colorectal cancer Biol. Res. Han,Xu; Wang,Lingling; Ning,Yu; Li,Shuang; Wang,Zhenjun. BACKGROUND AND OBJECTIVE: Long non-coding RNAs can regulate tumorigenesis of various cancers. Dys-regulation of lncRNA-AFAP1-AS1 has not been studied in colorectal carcinoma (CRC). This study was to examine the function involvement of AFAP1-AS1 in tumor growth and metastasis of CRC. METHODS: Relative expression of AFAP1-AS1 in CRC tissues and CRC cells lines was determined using quantitative real-time PCR (qRT-PCR). Functional involvement of AFAP1-AS1 in tumor proliferation and metastasis was evaluated in AFAP1-AS1-specific siRNA-treated CRC cells and in CRC cell xenograft. Expression of epithelial-mesenchymal transition (EMT)-related gene expression was determined using western blot. RESULTS: Relative expression of AFAP1-AS1 was significantly elevated in... Tipo: Journal article Palavras-chave: AFAP1-AS1; Colorectal cancer; Tumor metastasis; Epithelial-mesenchymal transition (EMT). Ano: 2016 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602016000100036 Registros recuperados: 1 Primeira ... 1 ... Última

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