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Registros recuperados: 14 | |
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Phillips,M.I.. |
Gene therapy for hypertension is needed for the next generation of antihypertensive drugs. Current drugs, although effective, have poor compliance, are expensive and short-lasting (hours or one day). Gene therapy offers a way to produce long-lasting antihypertensive effects (weeks, months or years). We are currently using two strategies: a) antisense oligodeoxynucleotides (AS-ODN) and b) antisense DNA delivered in viral vectors to inhibit genes associated with vasoconstrictive properties. It is not necessary to know all the genes involved in hypertension, since many years of experience with drugs show which genes need to be controlled. AS-ODN are short, single-stranded DNA that can be injected in naked form or in liposomes. AS-ODN, targeted to angiotensin... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Gene therapy; Hypertension; Antisense; Vectors. |
Ano: 2000 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000600013 |
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Ruiz García, Noé. |
La dispersión espacio-temporal del Citrus tristeza virus se caracterizó en Tamaulipas de diciembre de 2001 a marzo de 2004, en 11 huertos comerciales de naranja dulce injerta- dos en naranjo agrio. Adicionalmente, se comparó el desempeño de la técnica serológica inmunoimpresión-ELISA con respecto a DAS-ELISA propuesta en la normatividad ofi- cial mexicana de la Campaña Nacional contra CTV. El objetivo fue proporcionar bases epidemiológicas e incorporar criterios de diagnóstico viral en una propuesta de muestreo con fines de erradicación. Inmunoimpresión-ELISA fue tan confiable (97.8 %) como DAS-ELISA en identificar árboles positivos, siendo 54.9% más económica e implicó solo una sexta parte del tiempo de procesado. La detectabilidad en impresiones... |
Tipo: Tesis |
Palavras-chave: Citrus tristeza virus; Serología; Muestreo; Vectores; Epidemiología Citrus tristeza virus; Serology; Sampling; Vectors; Epidemiology. |
Ano: 2012 |
URL: http://hdl.handle.net/10521/1020 |
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Ruiz García, Noé. |
La dispersión espacio-temporal del Citrus tristeza virus se caracterizó en Tamaulipas de diciembre de 2001 a marzo de 2004, en 11 huertos comerciales de naranja dulce injerta- dos en naranjo agrio. Adicionalmente, se comparó el desempeño de la técnica serológica inmunoimpresión-ELISA con respecto a DAS-ELISA propuesta en la normatividad ofi- cial mexicana de la Campaña Nacional contra CTV. El objetivo fue proporcionar bases epidemiológicas e incorporar criterios de diagnóstico viral en una propuesta de muestreo con fines de erradicación. Inmunoimpresión-ELISA fue tan confiable (97.8 %) como DAS-ELISA en identificar árboles positivos, siendo 54.9% más económica e implicó solo una sexta parte del tiempo de procesado. La detectabilidad en impresiones... |
Tipo: Tesis |
Palavras-chave: Citrus tristeza virus; Serología; Muestreo; Vectores; Epidemiología; Doctorado; Fitopatología; Fitopatología; Serology; Sampling; Vectors; Epidemiology. |
Ano: 2008 |
URL: http://hdl.handle.net/10521/1348 |
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Silva,Allan Martins da. |
The results of larval collections of mosquitoes from artificial containers and natural breeding at urban and rural areas carried out at Sertaneja, northern State Paraná, Brazil, from February to April, 1995, are presented. Among the 4534 immature forms collected, belonging to 21 species or species-groups, the species with higher density were Aedes aegypti (Linnaeus, 1762), Aedes albopictus (Skuse, 1894), Culex quinquefasciatus Say, 1823 and Limatus durhami Theobald, 1901. |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Culicidae; Larvae; Vectors; Brazil. |
Ano: 2002 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0073-47212002000400005 |
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Galati,Eunice Aparecida Bianchi; Marassá,Ana Maria; Fonseca,Mauro Breviglieri; Gonçalves-Andrade,Rute Maria; Consales,Cleide Aschenbrenner; Bueno,Edna Fátima Maria. |
Phlebotomines (Diptera, Psychodidae) in the Speleological Province of the Ribeira Valley: 3. Area of hostels for tourists who visit the Parque Estadual do Alto Ribeira (PETAR), state of São Paulo, Brazil. The study characterizes some ecological aspects of the phlebotomine fauna in an endemic area of cutaneous leishmaniasis (CL) situated in the Serra district, Iporanga municipality where the hostels for tourists visiting the PETAR are located. Captures were undertaken on a smallholding and a small farm situated near the hostels, monthly between January/2001 and December/2003 with automatic light traps (ALT) in pigsty, hen-house and veranda of a domicile at the two sites, and in peridomicile of the small farm also with black/white Shannon traps. With the ALT... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ecology; Leishmaniases; Lutzomyia longipalpis; Phlebotominae; Vectors. |
Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0085-56262010000400020 |
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Galati,Eunice A. B.; Marassá,Ana Maria; Gonçalves-Andrade,Rute Maria; Bueno,Edna Fátima Maria; Paiva,Byanca R.; Malafronte,Rosely S.. |
Captures with black and white Shannon traps were undertaken to identify aspects of the behavior of the two cryptic and sympatric species implicated as vectors of cutaneous leishmaniasis, Nyssomyia intermedia (Lutz & Neiva, 1912) and Nyssomyia neivai (Pinto, 1926). The traps were installed side by side, monthly, from July 2001 to June 2002, from 18 to 07 hours, in a peridomicile of Iporanga municipality, state of São Paulo, Brazil. A total of 2,142 specimens were captured, Ny. intermedia (47.4%) and Ny. neivai (50.5%). The white trap was more attractive to both sexes of both species. Males of Ny. neivai predominated (70%) over those of Ny. intermedia on the two traps; on the black trap, the females of Ny. intermedia predominated (63.3%) over those... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ecology; Cutaneous leishmaniasis; Ribeira Valley; Vectors. |
Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0085-56262010000400021 |
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Galati,Eunice Aparecida Bianchi; Marassá,Ana Maria; Gonçalves-Andrade,Rute Maria; Consales,Cleide Aschenbrenner; Bueno,Edna F. M.. |
The identification of the sandfly fauna and investigation of some ecological aspects of its populations in areas frequented by tourists of the PEI, an Atlantic forest reserve with many caves, were the objective of this study. Captures were undertaken monthly from January 2001 to December 2002, with automatic light traps installed in 13 ecotopes, including caves, forests, domiciliary and peridomiciliary environments, and by aspiration in armadillo burrows. Additionally, although not at regular intervals, Shannon traps were installed in forests and anthropic environments, aspirations were made on cave walls, among roots and fallen leaves, and some insects were captured while biting researchers. A total of 891 sandflies belonging to 21 species were captured.... |
Tipo: Info:eu-repo/semantics/report |
Palavras-chave: Atlantic forest; Cave; Leishmaniasis; Vectors. |
Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0085-56262010000200015 |
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Galati,Eunice A. B.; Marassá,Ana Maria; Gonçalves-Andrade,Rute Maria; Consales,Cleide Aschenbrenner; Bueno,Edna Fátima Maria. |
The Parque Estadual do Alto Ribeira (PETAR) with about 250 caves, in an Atlantic forest reserve, is an important ecotourist attraction in the Ribeira Valley, an endemic area of American cutaneous leishmaniasis (ACL). With the purpose of investigating Leishmania vector species bothersome to humans the sandfly fauna was identified and some of its ecological aspects in the Santana nucleus, captures were undertaken monthly with automatic light traps in 11 ecotopes, including caves, forests, a camping site and domiciliary environments, and on black and white Shannon traps, from January/2001 to December/2002. A total of 2,449 sandflies representing 21 species were captured. The highest values of abundance obtained in the captures with automatic light traps were... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Caves; Ecology; Leishmaniasis; Sandfly; Vectors. |
Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0085-56262010000300020 |
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Registros recuperados: 14 | |
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