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Dias,Luciana Basili; Melhem,Márcia de Souza Carvalho; Szeszs,Maria Walderez; Meirelles Filho,José; Hahn,Rosane Christine. |
Causative agent in majority of VVC is Candida albicans, but infection due to non-C. albicans is common. Use of empiric antifungal therapy in Brazil due to syndromic management of vulvovaginitis could act as risk factor for increase resistance among VVC causative agents. From Mato Grosso patients, 160 with culture-proved among 404 women who had clinical symptoms of VVC, were enrolled in this study. 70 non-pregnant women and 90 pregnant women were included. Candida albicans was the most prevalent, representing 72.9% in the non-pregnant group and 92.3% in the pregnant group. Differences in species distribution were noted between the two groups, being C. parapsilosis the second more prevalent species among non-pregnant women. Susceptibility testing revealed... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Vulvovaginal candidiasis; Antifungal susceptibility testing; Antifungal agents; Candida albicans. |
Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000400009 |
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Brandolt,Tchana Martinez; Klafke,Gabriel Baracy; Gonçalves,Carla Vitola; Bitencourt,Laura Riffel; Martinez,Ana Maria Barral de; Mendes,Josiara Furtado; Meireles,Mário Carlos Araújo; Xavier,Melissa Orzechowski. |
Abstract Vulvovaginal candidiasis (VVC) is an infection of the genital mucosa caused by different species of the genus Candida. Considering the lack of data on this topic in the south of Brazil, this study aimed to assess the prevalence of Candida spp. in the cervical-vaginal mucosa of patients treated at a university hospital in southern Rio Grande do Sul, as well as the etiology and the susceptibility of the isolates against fluconazole, itraconazole, miconazole and nystatin. Samples were collected at the gynecology clinic of the Federal Hospital of the University of Rio Grande, and the isolates were identified using phenotypic and biochemical tests. The susceptibility analysis was performed according to the CLSI M27-A2 protocol. Of the 263 patients... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Vulvovaginal candidiasis; Antifungal; Susceptibility; Resistance. |
Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822017000100145 |
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Fornari,Gheniffer; Vicente,Vania Aparecida; Gomes,Renata Rodrigues; Muro,Marisol Dominguez; Pinheiro,Rosangela Lameira; Ferrari,Carolina; Herkert,Patricia Fernanda; Takimura,Marcos; Carvalho,Newton Sérgio de; Queiroz-Telles,Flavio. |
Abstract Vulvovaginal candidiasis affects women of reproductive age, which represents approximately 15–25% of vaginitis cases. The present study aimed to isolate and characterize yeast from the patients irrespective of the presentation of clinical symptoms. The isolates were subjected to in vitro susceptibility profile and characterization by molecular markers, which intended to assess the distribution of species. A total of 40 isolates were obtained and identified through the CHROMagar, API20aux and by ITS and D1/D2 regions sequencing of DNAr gene. Candida albicans strains were genotyped by the ABC system and the isolates were divided into two genotypic groups. The identity of the C. albicans, C. glabrata, C. guilliermondii, C. kefyr and Saccharomyces... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Vulvovaginal candidiasis; In vitro susceptibility; Variability genetic. |
Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822016000200373 |
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Shinobu,Cristiane Suemi; Ogatta,Sueli Fumie Yamada; Bizerra,Fenando; Furlaneto,Luciana; Peralta,Rosane Marina; Svidzinski,Terezinha Inez Estivalet; Consolaro,Marcia Edilaine Lopes. |
The physiopathogenesis of vulvovaginal candidiasis (VVC) is still not completely elucidated. The objective of this study was to evaluate if there is a relationship between the different genotypes of Candida albicans, their main agent and the virulence of this yeast in vaginal isolates, and to check if there are laboratorial markers that can predict the ability of each isolate to develop VVC independently of symptoms. The production of exoenzymes protease, phospholipase and haemolysin, resistance to hydrogen peroxide, and the genotype were determined. Genotype A was predominant (75%), protease, phospholipase and haemolytic activity were highly expressed, and the majority of the yeasts were sensitive to H2O2 in 1 and 2 hours of exposure, suggesting that... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: C. albicans; Vulvovaginal candidiasis; Genotype; Virulence factors. |
Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822007000300015 |
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Storti-Filho,Agenor; Damke,Edilson; Carrara,Márcia Aparecida; Batista,Marcia Regina; Donatti,Lucélia; Boer,Cinthia Gandolfi; Svizdinski,Terezinha Inez Estivalet; Consolaro,Márcia Edilaine Lopes. |
The objective of this study was to determine the effect of medroxyprogesterone acetate (DMPA) on the development and maintenance of Candida albicans in the vagina of oophorectomized Wistar rats. The animals were divided into negative control groups (NCG), which received injections of sterile saline; positive control groups (PCG), which were given injections of estradiol valerate; and progesterone groups (PG), which were given injections of Depo-Provera®. After one week of hormonal induction, vaginal infection by C. albicans was induced in all the groups and detected by vaginal yeast culture and Papanicolaou smear. In addition, scanning and transmission electron microscopy images were obtained to confirm the vaginal infection by yeast in PG. A difference in... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Depomedroxyprogesterone acetate/effects; Depomedroxyprogesterone acetate/experimental study; Vulvovaginal candidiasis; Candida albicans. |
Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000100021 |
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