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	Provedor de dados BJMBR (1) Autor Barbosa,A.L.R. (1) Moraes,M.O. (1) Oliveira,G.J. (1) Pinheiro,C.A. (1) Ribeiro,R.A. (1) Souza,M.H.L.P. (1) Torres,J.N.L. (1) Vale,M.L. (1) Mais... Palavra-chave Carrageenan (1) Hypernociception (1) Nitric oxide (1) Walker 246 tumor-bearing rats (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2012 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Participation of the NO/cGMP/K+ATP pathway in the antinociception induced by Walker tumor bearing in rats BJMBR Barbosa,A.L.R.; Pinheiro,C.A.; Oliveira,G.J.; Torres,J.N.L.; Moraes,M.O.; Ribeiro,R.A.; Vale,M.L.; Souza,M.H.L.P.. Implantation of Walker 256 tumor decreases acute systemic inflammation in rats. Inflammatory hyperalgesia is one of the most important events of acute inflammation. The L-arginine/NO/cGMP/K+ATP pathway has been proposed as the mechanism of peripheral antinociception mediated by several drugs and physical exercise. The objective of this study was to investigate a possible involvement of the NO/cGMP/K+ATP pathway in antinociception induced in Walker 256 tumor-bearing male Wistar rats (180-220 g). The groups consisted of 5-6 animals. Mechanical inflammatory hypernociception was evaluated using an electronic version of the von Frey test. Walker tumor (4th and 7th day post-implantation) reduced prostaglandin E2- (PGE2, 400 ng/paw; 50 µL; intraplantar injection)... Tipo: Info:eu-repo/semantics/article Palavras-chave: Walker 246 tumor-bearing rats; Hypernociception; Nitric oxide; Carrageenan. Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000600009 Registros recuperados: 1 Primeira ... 1 ... Última

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