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Crude ethanol extract from babassu (Orbignya speciosa): cytotoxicity on tumoral and non-tumoral cell lines 42
Rennó,Magdalena N.; Barbosa,Gleyce M.; Zancan,Patricia; Veiga,Venicio F.; Alviano,Celuta S.; Sola-Penna,Mauro; Menezes,Fábio S.; Holandino,Carla.
Plant-derived substances have been considered as important sources of drugs, including antineoplasic agents. Babassu mesocarp is popularly used in Brazil as a food additive, and in popular medicine against several conditions, such as inflammations, menstrual pains and leukaemia. From babassu Orbignya speciosa (Mart.) Barb. Rodr. [Arecaceae (Palmae)] epicarp/mesocarp, an ethanol extract was prepared and named OSEME, which was tested on the viability,morphology and metabolism of several cell lines, such as the leukaemic cell lines, HL-60, K562 and the latter multidrug resistant counterpart K562-Lucena 1, the human breast cancer cell line MCF-7, the mouse fibroblast cell line 3T3-L1 and fresh human lymphocytes. OSEME promoted a dose-dependent decrease on the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antitumoral agents; Ethanol extract; Orbignya speciosa.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652008000300008
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Phytotoxic potential of Senna occidentalis and Senna obtusifolia - doi: 10.4025/actascibiolsci.v32i3.5833 3
Peres, Marize Terezinha Lopes Pereira; UFMS; Cândido, Ana Carina da Silva; UFMS; Bonilla, Marilia Bisacotti; UFMS; Faccenda, Odival; UEMS; Hess, Sônia Corina; UFMS.
This work aimed to investigate the phytotoxic potential of the aerial and underground parts of Senna occidentalis and S. obtusifolia on the germination and initial growth of lettuce and onion. Four concentrations were used of each ethanol extract (0, 250, 500 and 1000 mg L-1), with four replications of 50 seeds. From the investigated species, the aerial part of S. occidentalis interfered in onion germination and the aerial part of S. obtusifolia interfered in the germinations of lettuce and onion. The ethanol extract from the aerial and underground parts of the studied species inhibited the root growth of lettuce and onion. The hypocotyl/coleoptile growth in lettuce and onion was inhibited by the extract of S. obtusifolia aerial part and the underground...
Palavras-chave: Ethanol extract; Leguminosae; Weeds ethanol extract; Leguminosae; Weeds.
Ano: 2010 URL: http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/5833
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Antifeeding and Insecticide Properties of Aqueous and Ethanolic Fruit Extracts from Melia azedarach L.on the Elm Leaf Beetle Xanthogaleruca luteola Müller 117
Chiffelle,Italo; Huerta,Amanda; Azúa,Fernando; Puga,Karla; Araya,Jaime E.
Xanthogaleruca luteola Müller (Coleoptera: Chrysomelidae), a defoliator of Ulmus species currently present in several regions of central Chile, causes severe damage to trees, mainly in park areas, street tree-lines and gardens. The antifeeding and insecticidal activities of extracts from immature fruit of Melia azedarach L. (Meliaceae) were determined on adults of X. luteola in laboratory bioassays. Several concentrations of the extracts obtained with water and ethanol were used and their effectiveness and LC50 were determined. The antifeeding action of the water extracts caused 100% deterrence over concentrations of 3.6% w/v. Both extracts were effective insecticides against adults, causing 86% mortality (2.4% w/v), with a better performance of the...
Tipo: Journal article Palavras-chave: Botanical insecticides; Ethanol extract; Water extract.
Ano: 2011 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-58392011000200006
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Effects of Thai piperaceae plant extracts on Neospora caninum infection 19
Leesombun, Arpron; Boonmasawai, Sookruetai; Nishikawa, Yoshifumi.
Neosporosis has a worldwide distribution and causes economic losses in farming, particularly by increasing the risk of abortion in cattle. This study investigated the effects of Thai piperaceae (Piper betle, P. nigrum, and P. sarmentosum) extracts on Neospora caninum infections in vitro and in vivo. In an in vitro parasite growth assay based on the green fluorescent protein (GFP) signal, P. betle was the most effective extract at inhibiting parasite growth in human foreskin fibroblast cells (IC50 of GFP-expressing N. caninum parasites, 22.1 mu g/ml). The P. betle extract, at 25 mu g per ml, inhibited parasite invasion into host cells. Furthermore, in two independent experiments, treating N. caninum-infected mice with the P. betle extract for 7 days...
Palavras-chave: Neospora caninum; Neosporosis; Piper betle; Piper nigrum; Piper sarmentosum; Ethanol extract.
Ano: 2017 URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4578
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Linderae radix ethanol extract attenuates alcoholic liver injury via attenuating inflammation and regulating gut microbiota in rats 56
Lou,Zhaohuan; Wang,Junwei; Chen,Yingjun; Xu,Chandi; Chen,Xinyi; Shao,Tiejuan; Zhang,Kena; Pan,Hongying.
This study aimed to explore the influence of gut microbiota alterations induced by Linderae radix ethanol extract (LREE) on alcoholic liver disease (ALD) in rats and to study the anti-inflammatory effect of LREE on ALD through the lipopolysaccharide (LPS) toll-like receptor 4 (TLR4)-nuclear factor kappa B (NF-κB) pathway. ALD rat models were established by intragastric liquor [50% (v/v) ethanol] administration at 10 mL/kg body weight for 20 days. Rats were divided into six groups: normal group (no treatment), model group (ALD rats), Essentiale group (ALD rats fed with Essentiale, 137 mg/kg), and LREE high/moderate/low dose groups (ALD rats fed with 4, 2, or 1 g LREE/kg). NF-κB and LPS levels were evaluated. Liver pathological changes and intestinal...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Lindera aggregata (Sims) Kosterm; Ethanol extract; Alcoholic liver disease; Intestinal endotoxemia; 16S ribosomal RNA gene sequencing; Tight junction protein.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000600601
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